AmiGO 2: Term Details for "Mre11 complex" (GO:0030870)

Accession: GO:0030870
Name: Mre11 complex
Ontology: cellular_component
Synonyms: MRN complex, MRX complex, RAD50-MRE11-NBN complex, RMX complex, Rad50 complex, Rad50-Rad32-Nbs1 complex
Alternate IDs: None
Definition: Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins. Source: GOC:vw, PMID:11988766, GOC:mah, PMID:17674145
Comment: None
History: See term history for GO:0030870 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to Mre11 complex (excluding "regulates").; Link to all direct and indirect annotations to Mre11 complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for Mre11 complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
Mre11 complex	RO:0002162	Eukaryota (NCBITaxon:2759)
Mre11 complex	is_a	nuclear protein-containing complex (GO:0140513)

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