1q25

X-ray diffraction
1.8Å resolution

Crystal structure of N-terminal 3 domains of CI-MPR

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-139951 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Cation-independent mannose-6-phosphate receptor Chain: A
Molecule details ›
Chain: A
Length: 432 amino acids
Theoretical weight: 47.62 KDa
Source organism: Bos taurus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P08169 (Residues: 45-476; Coverage: 18%)
Gene names: IGF2R, M6P
Sequence domains: Cation-independent mannose-6-phosphate receptor repeat
Structure domains: Mannose-6-phosphate receptor binding domain

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-ID-B
Spacegroup: P212121
Unit cell:
a: 61.157Å b: 84.746Å c: 96.051Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.235 0.235 0.283
Expression system: Trichoplusia ni