AmiGO 2: Term Details for "immunological synapse formation" (GO:0001771)

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Term Information

Accession: GO:0001771
Name: immunological synapse formation
Ontology: biological_process
Synonyms: formation of immunological synapse
Alternate IDs: None
Definition: The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction. Source: PMID:11244041, GOC:mgi_curators, PMID:11376330
Comment: None
History: See term history for GO:0001771 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to immunological synapse formation (excluding "regulates").; Link to all direct and indirect annotations to immunological synapse formation (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for immunological synapse formation (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0032501 multicellular organismal process
GO:0001775 cell activation
GO:0002376 immune system process
GO:0008037 cell recognition
GO:0045321 leukocyte activation
GO:0009988 cell-cell recognition
GO:0046649 lymphocyte activation
GO:0001771 immunological synapse formation
GO:2000521 negative regulation of immunological synapse formation
GO:2000526 positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
GO:2000522 positive regulation of immunological synapse formation
GO:2000520 regulation of immunological synapse formation

Parents of immunological synapse formation (GO:0001771)

subject	relation	object
immunological synapse formation	BFO:0000050	lymphocyte activation (GO:0046649)
immunological synapse formation	RO:0002162	Vertebrata (NCBITaxon:7742)
immunological synapse formation	is_a	cell-cell recognition (GO:0009988)

Children of immunological synapse formation (GO:0001771)

subject	relation	object
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation (GO:2000526)	BFO:0000050	immunological synapse formation
negative regulation of immunological synapse formation (GO:2000521)	RO:0002212	immunological synapse formation
positive regulation of immunological synapse formation (GO:2000522)	RO:0002213	immunological synapse formation
regulation of immunological synapse formation (GO:2000520)	RO:0002211	immunological synapse formation

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