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long-chain fatty acid-CoA ligase activity

Term Information

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Accession
GO:0004467
Name
long-chain fatty acid-CoA ligase activity
Ontology
molecular_function
Synonyms
long-chain acyl-CoA synthetase activity, long-chain-fatty-acid-CoA ligase activity, long-chain-fatty-acyl-CoA synthetase activity, LCFA synthetase activity, acyl-CoA ligase activity, acyl-CoA synthetase activity, fatty acid thiokinase (long-chain) activity, lignoceroyl-CoA synthase activity, long chain fatty acyl-CoA synthetase activity, long-chain acyl CoA synthetase activity, long-chain acyl-coenzyme A synthetase activity, long-chain fatty acid activation, long-chain fatty acyl coenzyme A synthetase activity, thiokinase, pristanoyl-CoA synthetase, stearoyl-CoA synthetase, acyl-activating enzyme activity
Alternate IDs
GO:0003996
Definition
Catalysis of the reaction: a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. Source: RHEA:15421
Comment
While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283). Note that this term has a MetaCyc pathway reference as the pathway only has a single step.
History
See term history for GO:0004467 at QuickGO
Chem. react.
has participant ATP(4-)
has participant long-chain fatty acyl-CoA(4-)
has participant coenzyme A(4-)
has participant long-chain fatty acid anion
has participant diphosphate(3-)
has participant adenosine 5'-monophosphate(2-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of long-chain fatty acid-CoA ligase activity (GO:0004467)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
long-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  ATP(4-) (CHEBI:30616)
long-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  long-chain fatty acyl-CoA(4-) (CHEBI:83139)
long-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  coenzyme A(4-) (CHEBI:57287)
long-chain fatty acid-CoA ligase activity [BFO:0000050 relation] BFO:0000050  long-chain fatty acid metabolic process (GO:0001676)
long-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  long-chain fatty acid anion (CHEBI:57560)
long-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  diphosphate(3-) (CHEBI:33019)
long-chain fatty acid-CoA ligase activity [is_a relation] is_a  fatty acid-CoA ligase activity (GO:0120515)
long-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  adenosine 5'-monophosphate(2-) (CHEBI:456215)
Children of long-chain fatty acid-CoA ligase activity (GO:0004467)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
myristoyl-CoA ligase activity (GO:0090432) [is_a relation] is_a  long-chain fatty acid-CoA ligase activity
oleoyl-CoA ligase activity (GO:0090434) [is_a relation] is_a  long-chain fatty acid-CoA ligase activity
arachidonate-CoA ligase activity (GO:0047676) [is_a relation] is_a  long-chain fatty acid-CoA ligase activity
palmitoyl-CoA ligase activity (GO:0090433) [is_a relation] is_a  long-chain fatty acid-CoA ligase activity