AmiGO 2: Term Details for "ribose phosphate diphosphokinase activity" (GO:0004749)

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Term Information

Accession: GO:0004749
Name: ribose phosphate diphosphokinase activity
Ontology: molecular_function
Synonyms: ribose-phosphate pyrophosphokinase activity, 5-phosphoribose pyrophosphorylase activity, 5-phosphoribosyl-1-pyrophosphate synthetase activity, 5-phosphoribosyl-alpha-1-pyrophosphate synthetase activity, ATP:D-ribose-5-phosphate diphosphotransferase activity, PP-ribose P synthetase activity, PPRibP synthetase activity, PRPP synthetase activity, phosphoribosyl diphosphate synthetase activity, phosphoribosyl pyrophosphate synthetase activity, phosphoribosyl-diphosphate synthetase activity, phosphoribosylpyrophosphate synthase activity, phosphoribosylpyrophosphate synthetase activity, pyrophosphoribosylphosphate synthetase activity, ribophosphate pyrophosphokinase activity, ribose-5-phosphate pyrophosphokinase activity, ribose-phosphate diphosphokinase activity
Alternate IDs: None
Definition: Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H+. Source: RHEA:15609
Comment: Note that this term has a MetaCyc pathway reference as the pathway only has a single step.
History: See term history for GO:0004749 at QuickGO
Chem. react.: has participant ATP(4-); has participant adenosine 5'-monophosphate(2-); has participant 5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-); has participant hydron; has participant D-ribofuranose 5-phosphate(2-)
Subset: None
Related: Link to all genes and gene products annotated to ribose phosphate diphosphokinase activity (excluding "regulates").; Link to all direct and indirect annotations to ribose phosphate diphosphokinase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for ribose phosphate diphosphokinase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016778 diphosphotransferase activity
GO:0004749 ribose phosphate diphosphokinase activity
GO:0002189 ribose phosphate diphosphokinase complex

Parents of ribose phosphate diphosphokinase activity (GO:0004749)

subject	relation	object
ribose phosphate diphosphokinase activity	RO:0000057	ATP(4-) (CHEBI:30616)
ribose phosphate diphosphokinase activity	RO:0000057	adenosine 5'-monophosphate(2-) (CHEBI:456215)
ribose phosphate diphosphokinase activity	RO:0000057	5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-) (CHEBI:58017)
ribose phosphate diphosphokinase activity	RO:0000057	hydron (CHEBI:15378)
ribose phosphate diphosphokinase activity	RO:0000057	D-ribofuranose 5-phosphate(2-) (CHEBI:78346)
ribose phosphate diphosphokinase activity	is_a	diphosphotransferase activity (GO:0016778)

Children of ribose phosphate diphosphokinase activity (GO:0004749)

subject	relation	object
ribose phosphate diphosphokinase complex (GO:0002189)	RO:0002215	ribose phosphate diphosphokinase activity

EC: 2.7.6.1
KEGG_REACTION: R01049
MetaCyc: PRPPSYN-RXN; PWY0-662
Reactome: R-HSA-73580; R-HSA-111215
RHEA: 15609