AmiGO 2: Term Details for "activation-induced cell death of T cells" (GO:0006924)

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Term Information

Accession: GO:0006924
Name: activation-induced cell death of T cells
Ontology: biological_process
Synonyms: activation-induced cell death of T lymphocytes, activation-induced cell death of T-cells, activation-induced cell death of T-lymphocytes, AICD, activated T cell apoptosis, antigen-driven apoptosis
Alternate IDs: None
Definition: A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors. Source: ISBN:0781765196, PMID:12752672, GOC:add, PMID:12414721, GOC:mtg_apoptosis
Comment: None
History: See term history for GO:0006924 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to activation-induced cell death of T cells (excluding "regulates").; Link to all direct and indirect annotations to activation-induced cell death of T cells (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for activation-induced cell death of T cells (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
CARO:0000006 material anatomical entity
GO:0008150 biological_process
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
UBERON:0000061 anatomical structure
GO:0048870 cell motility
GO:0009987 cellular process
UBERON:0034923 disconnected anatomical group
GO:0002376 immune system process
GO:0050896 response to stimulus
CL:0000000 cell
GO:0008219 cell death
GO:0016477 cell migration
CL:0000255 eukaryotic cell
GO:0042592 homeostatic process
GO:0002252 immune effector process
GO:0006955 immune response
GO:0032501 multicellular organismal process
UBERON:0015203 non-connected functional system
CL:0002242 nucleate cell
GO:0002250 adaptive immune response
GO:0001667 ameboidal-type cell migration
CL:0000988 hematopoietic cell
UBERON:0002405 immune system
CL:0000738 leukocyte
GO:0002443 leukocyte mediated immunity
CL:0000219 motile cell
GO:0048871 multicellular organismal-level homeostasis
GO:0012501 programmed cell death
CL:0000226 single nucleate cell
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
GO:0006915 apoptotic process
GO:0048872 homeostasis of number of cells
GO:0002449 lymphocyte mediated immunity
CL:0000842 mononuclear cell
GO:0071887 leukocyte apoptotic process
GO:0001776 leukocyte homeostasis
CL:0000542 lymphocyte
GO:0002456 T cell mediated immunity
GO:0070227 lymphocyte apoptotic process
GO:0002260 lymphocyte homeostasis
CL:0000084 T cell
GO:0070231 T cell apoptotic process
GO:0043029 T cell homeostasis
GO:0006924 activation-induced cell death of T cells
GO:0070236 negative regulation of activation-induced cell death of T cells
GO:0070237 positive regulation of activation-induced cell death of T cells
GO:0070235 regulation of activation-induced cell death of T cells

Parents of activation-induced cell death of T cells (GO:0006924)

subject	relation	object
activation-induced cell death of T cells	is_a	T cell apoptotic process (GO:0070231)
activation-induced cell death of T cells	RO:0002162	Vertebrata (NCBITaxon:7742)
activation-induced cell death of T cells	BFO:0000050	T cell homeostasis (GO:0043029)

Children of activation-induced cell death of T cells (GO:0006924)

subject	relation	object
positive regulation of activation-induced cell death of T cells (GO:0070237)	RO:0002213	activation-induced cell death of T cells
negative regulation of activation-induced cell death of T cells (GO:0070236)	RO:0002212	activation-induced cell death of T cells
regulation of activation-induced cell death of T cells (GO:0070235)	RO:0002211	activation-induced cell death of T cells

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