site of DSB, DNA damage foci, DNA damage focus, IRIF, ionizing radiation-induced foci
Alternate IDs
None
Definition
A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.
Source:PMID:21035408,
GOC:vw,
GOC:bf,
PMID:20096808,
GOC:mah