AmiGO 2: Term Details for "protein targeting to ER" (GO:0045047)

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Term Information

Accession: GO:0045047
Name: protein targeting to ER
Ontology: biological_process
Synonyms: protein targeting to endoplasmic reticulum, protein-ER targeting, protein-endoplasmic reticulum targeting
Alternate IDs: None
Definition: The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane. Source: ISBN:0716731363
Comment: None
History: See term history for GO:0045047 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to protein targeting to ER (excluding "regulates").; Link to all direct and indirect annotations to protein targeting to ER (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for protein targeting to ER (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0051179 localization
GO:0051641 cellular localization
GO:0033036 macromolecule localization
GO:0070727 cellular macromolecule localization
GO:0008104 protein localization
GO:0051234 establishment of localization
GO:0045184 establishment of protein localization
GO:0033365 protein localization to organelle
GO:0072594 establishment of protein localization to organelle
GO:0070972 protein localization to endoplasmic reticulum
GO:0072599 establishment of protein localization to endoplasmic reticulum
GO:0006605 protein targeting
GO:0045047 protein targeting to ER
GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane
GO:0006614 SRP-dependent cotranslational protein targeting to membrane

Parents of protein targeting to ER (GO:0045047)

subject	relation	object
protein targeting to ER	is_a	protein targeting (GO:0006605)
protein targeting to ER	is_a	establishment of protein localization to endoplasmic reticulum (GO:0072599)
protein targeting to ER	RO:0002339	endoplasmic reticulum (GO:0005783)

Children of protein targeting to ER (GO:0045047)

subject	relation	object
post-translational protein targeting to endoplasmic reticulum membrane (GO:0006620)	is_a	protein targeting to ER
SRP-dependent cotranslational protein targeting to membrane (GO:0006614)	is_a	protein targeting to ER

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