AmiGO 2: Term Details for "Lsm1-7-Pat1 complex" (GO:1990726)

Term Information

Accession: GO:1990726
Name: Lsm1-7-Pat1 complex
Ontology: cellular_component
Synonyms: None
Alternate IDs: None
Definition: A conserved, heteroheptameric, cytoplasmic protein complex composed of Lsm1, Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Pat1, or orthologs thereof, that shows a strong binding preference for oligoadenylated RNAs over polyadenylated RNAs. May bind further associated proteins. Facilitates the deadenylation-dependent decapping of mRNA in the P-body thereby regulating mRNA decay and subsequent degradation by the 5' to 3' pathway. Source: GOC:krc, PMID:23620288, PMID:24139796, PMID:28768202, PMID:27627834, PMID:19121818, GOC:bhm
Comment: None
History: See term history for GO:1990726 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to Lsm1-7-Pat1 complex (excluding "regulates").; Link to all direct and indirect annotations to Lsm1-7-Pat1 complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for Lsm1-7-Pat1 complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0008152 metabolic process
GO:0048519 negative regulation of biological process
GO:0050794 regulation of cellular process
GO:0009058 biosynthetic process
GO:0043170 macromolecule metabolic process
GO:0048523 negative regulation of cellular process
GO:0044238 primary metabolic process
GO:0019222 regulation of metabolic process
GO:0009056 catabolic process
GO:0009059 macromolecule biosynthetic process
GO:0009892 negative regulation of metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:0009889 regulation of biosynthetic process
GO:0060255 regulation of macromolecule metabolic process
GO:0010467 gene expression
GO:0009057 macromolecule catabolic process
GO:0009890 negative regulation of biosynthetic process
GO:0010605 negative regulation of macromolecule metabolic process
GO:0090304 nucleic acid metabolic process
GO:0034655 nucleobase-containing compound catabolic process
GO:0010556 regulation of macromolecule biosynthetic process
GO:0005575 cellular_component
GO:0010558 negative regulation of macromolecule biosynthetic process
GO:0141188 nucleic acid catabolic process
GO:0010468 regulation of gene expression
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
GO:0010629 negative regulation of gene expression
GO:0032991 protein-containing complex
GO:0006401 RNA catabolic process
GO:0006402 mRNA catabolic process
GO:0120114 Sm-like protein family complex
GO:1990726 Lsm1-7-Pat1 complex

Parents of Lsm1-7-Pat1 complex (GO:1990726)

subject	relation	object
Lsm1-7-Pat1 complex	is_a	Sm-like protein family complex (GO:0120114)
Lsm1-7-Pat1 complex	RO:0002216	mRNA catabolic process (GO:0006402)

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