cofactor |
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CHEBI:23357 |
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An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group). |
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This entity has been manually annotated by the ChEBI Team.
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Outgoing
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cofactor
(CHEBI:23357)
is a
biochemical role
(CHEBI:52206)
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Incoming
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β-carotene
(CHEBI:17579)
has role
cofactor
(CHEBI:23357)
(6R)-5,10-methylenetetrahydrofolate(2−)
(CHEBI:15636)
has role
cofactor
(CHEBI:23357)
(6R)-5,10-methylenetetrahydrofolic acid
(CHEBI:1989)
has role
cofactor
(CHEBI:23357)
(6S)-5,6,7,8-tetrahydrofolate(2−)
(CHEBI:57453)
has role
cofactor
(CHEBI:23357)
(6S)-5,6,7,8-tetrahydrofolic acid
(CHEBI:15635)
has role
cofactor
(CHEBI:23357)
(R)-lipoate
(CHEBI:83088)
has role
cofactor
(CHEBI:23357)
(R)-lipoic acid
(CHEBI:30314)
has role
cofactor
(CHEBI:23357)
1,4-benzoquinone
(CHEBI:16509)
has role
cofactor
(CHEBI:23357)
3'-hydroxyechinenone
(CHEBI:80214)
has role
cofactor
(CHEBI:23357)
5,6,7,8-tetrahydropteridine
(CHEBI:28889)
has role
cofactor
(CHEBI:23357)
5-hydroxybenzimidazolylcob(I)amide
(CHEBI:17679)
has role
cofactor
(CHEBI:23357)
5-hydroxybenzimidazolylcob(I)amide(1−)
(CHEBI:60494)
has role
cofactor
(CHEBI:23357)
6,7-dimethyl-8-(1-D-ribityl)lumazine
(CHEBI:17601)
has role
cofactor
(CHEBI:23357)
6,7-dimethyl-8-(1-D-ribityl)lumazine(1−)
(CHEBI:58201)
has role
cofactor
(CHEBI:23357)
6-decylubiquinone
(CHEBI:52020)
has role
cofactor
(CHEBI:23357)
6-hydroxy-FAD
(CHEBI:40260)
has role
cofactor
(CHEBI:23357)
6-hydroxy-FAD(3−)
(CHEBI:60470)
has role
cofactor
(CHEBI:23357)
myo-inositol hexakisphosphate
(CHEBI:17401)
has role
cofactor
(CHEBI:23357)
myo-inositol hexakisphosphate(12−)
(CHEBI:58130)
has role
cofactor
(CHEBI:23357)
S-adenosyl-L-homocysteine
(CHEBI:16680)
has role
cofactor
(CHEBI:23357)
S-adenosyl-L-methionine
(CHEBI:15414)
has role
cofactor
(CHEBI:23357)
S-adenosyl-L-methionine zwitterion
(CHEBI:59789)
has role
cofactor
(CHEBI:23357)
L-ascorbate
(CHEBI:38290)
has role
cofactor
(CHEBI:23357)
L-ascorbic acid
(CHEBI:29073)
has role
cofactor
(CHEBI:23357)
adenosine 5'-monophosphate
(CHEBI:16027)
has role
cofactor
(CHEBI:23357)
adenosine 5'-monophosphate(2−)
(CHEBI:456215)
has role
cofactor
(CHEBI:23357)
ammonium
(CHEBI:28938)
has role
cofactor
(CHEBI:23357)
ATP
(CHEBI:15422)
has role
cofactor
(CHEBI:23357)
ATP(3−)
(CHEBI:57299)
has role
cofactor
(CHEBI:23357)
ATP(4−)
(CHEBI:30616)
has role
cofactor
(CHEBI:23357)
bacillithiol
(CHEBI:61338)
has role
cofactor
(CHEBI:23357)
barium(2+)
(CHEBI:37136)
has role
cofactor
(CHEBI:23357)
biotin
(CHEBI:15956)
has role
cofactor
(CHEBI:23357)
biotinate
(CHEBI:57586)
has role
cofactor
(CHEBI:23357)
bis(molybdopterin)tungsten cofactor
(CHEBI:30402)
has role
cofactor
(CHEBI:23357)
cadmium(2+)
(CHEBI:48775)
has role
cofactor
(CHEBI:23357)
calcium(2+)
(CHEBI:29108)
has role
cofactor
(CHEBI:23357)
cerium(3+)
(CHEBI:48782)
has role
cofactor
(CHEBI:23357)
chloride
(CHEBI:17996)
has role
cofactor
(CHEBI:23357)
chlorophyll a
(CHEBI:18230)
has role
cofactor
(CHEBI:23357)
chlorophyll a(1−)
(CHEBI:58416)
has role
cofactor
(CHEBI:23357)
chlorophyll b
(CHEBI:27888)
has role
cofactor
(CHEBI:23357)
chlorophyll b(1−)
(CHEBI:61721)
has role
cofactor
(CHEBI:23357)
cob(I)alamin
(CHEBI:15982)
has role
cofactor
(CHEBI:23357)
cob(I)alamin(1−)
(CHEBI:60488)
has role
cofactor
(CHEBI:23357)
cob(II)alamin
(CHEBI:16304)
has role
cofactor
(CHEBI:23357)
cobalamin
(CHEBI:30411)
has role
cofactor
(CHEBI:23357)
cobalt(2+)
(CHEBI:48828)
has role
cofactor
(CHEBI:23357)
cobalt(3+)
(CHEBI:49415)
has role
cofactor
(CHEBI:23357)
cobamamide
(CHEBI:18408)
has role
cofactor
(CHEBI:23357)
coenzyme F430
(CHEBI:28265)
has role
cofactor
(CHEBI:23357)
coenzyme F430(5−)
(CHEBI:60540)
has role
cofactor
(CHEBI:23357)
copper cation
(CHEBI:23378)
has role
cofactor
(CHEBI:23357)
copper(1+)
(CHEBI:49552)
has role
cofactor
(CHEBI:23357)
copper(2+)
(CHEBI:29036)
has role
cofactor
(CHEBI:23357)
corrin
(CHEBI:33221)
has role
cofactor
(CHEBI:23357)
corrinoid
(CHEBI:33913)
has role
cofactor
(CHEBI:23357)
decylplastoquinone
(CHEBI:72953)
has role
cofactor
(CHEBI:23357)
dehydro-D-arabinono-1,4-lactone
(CHEBI:17803)
has role
cofactor
(CHEBI:23357)
dihydrogenvanadate
(CHEBI:35169)
has role
cofactor
(CHEBI:23357)
dihydrolipoamide
(CHEBI:17694)
has role
cofactor
(CHEBI:23357)
dipyrromethane cofactor
(CHEBI:42121)
has role
cofactor
(CHEBI:23357)
dipyrromethane cofactor(4−)
(CHEBI:60342)
has role
cofactor
(CHEBI:23357)
divinyl chlorophyll a
(CHEBI:73113)
has role
cofactor
(CHEBI:23357)
divinyl chlorophyll a(1−)
(CHEBI:73095)
has role
cofactor
(CHEBI:23357)
divinyl chlorophyll b
(CHEBI:73115)
has role
cofactor
(CHEBI:23357)
divinyl chlorophyll b(1−)
(CHEBI:73096)
has role
cofactor
(CHEBI:23357)
echinenone
(CHEBI:4746)
has role
cofactor
(CHEBI:23357)
FAD
(CHEBI:16238)
has role
cofactor
(CHEBI:23357)
FAD(3−)
(CHEBI:57692)
has role
cofactor
(CHEBI:23357)
Fe-coproporphyrin III
(CHEBI:60454)
has role
cofactor
(CHEBI:23357)
Fe-coproporphyrin III(4−)
(CHEBI:68438)
has role
cofactor
(CHEBI:23357)
Fe4S2O2 iron-sulfur-oxygen cluster
(CHEBI:60519)
has role
cofactor
(CHEBI:23357)
ferriheme a
(CHEBI:36183)
has role
cofactor
(CHEBI:23357)
ferriheme a(1−)
(CHEBI:60532)
has role
cofactor
(CHEBI:23357)
ferroheme b
(CHEBI:17627)
has role
cofactor
(CHEBI:23357)
ferroheme b(2−)
(CHEBI:60344)
has role
cofactor
(CHEBI:23357)
ferroheme c(2−)
(CHEBI:61717)
has role
cofactor
(CHEBI:23357)
ferroheme c
(CHEBI:60562)
has role
cofactor
(CHEBI:23357)
flavin adenine dinucleotide
(CHEBI:24040)
has role
cofactor
(CHEBI:23357)
flavin mononucleotide
(CHEBI:24041)
has role
cofactor
(CHEBI:23357)
FMN
(CHEBI:17621)
has role
cofactor
(CHEBI:23357)
FMN(3−)
(CHEBI:58210)
has role
cofactor
(CHEBI:23357)
FMNH2
(CHEBI:16048)
has role
cofactor
(CHEBI:23357)
FMNH2(2−)
(CHEBI:57618)
has role
cofactor
(CHEBI:23357)
glutathionate(1−)
(CHEBI:57925)
has role
cofactor
(CHEBI:23357)
glutathione
(CHEBI:16856)
has role
cofactor
(CHEBI:23357)
heme d cis-diol
(CHEBI:62811)
has role
cofactor
(CHEBI:23357)
heme d cis-diol(2−)
(CHEBI:62814)
has role
cofactor
(CHEBI:23357)
heme o
(CHEBI:24480)
has role
cofactor
(CHEBI:23357)
hydrogen peroxide
(CHEBI:16240)
has role
cofactor
(CHEBI:23357)
hydrogencarbonate
(CHEBI:17544)
has role
cofactor
(CHEBI:23357)
hydrogenphosphate
(CHEBI:43474)
has role
cofactor
(CHEBI:23357)
hydroquinone
(CHEBI:17594)
has role
cofactor
(CHEBI:23357)
iron cation
(CHEBI:24875)
has role
cofactor
(CHEBI:23357)
iron(2+)
(CHEBI:29033)
has role
cofactor
(CHEBI:23357)
iron(3+)
(CHEBI:29034)
has role
cofactor
(CHEBI:23357)
iron-sulfur-iron cofactor
(CHEBI:60504)
has role
cofactor
(CHEBI:23357)
iron-sulfur-molybdenum cofactor
(CHEBI:30409)
has role
cofactor
(CHEBI:23357)
iron-sulfur-vanadium cofactor
(CHEBI:60357)
has role
cofactor
(CHEBI:23357)
lanthanum cation
(CHEBI:231841)
has role
cofactor
(CHEBI:23357)
lanthanum(3+)
(CHEBI:49701)
has role
cofactor
(CHEBI:23357)
lead(2+)
(CHEBI:49807)
has role
cofactor
(CHEBI:23357)
magnesium(2+)
(CHEBI:18420)
has role
cofactor
(CHEBI:23357)
manganese(2+)
(CHEBI:29035)
has role
cofactor
(CHEBI:23357)
menaquinone-7
(CHEBI:44245)
has role
cofactor
(CHEBI:23357)
methylcobalamin
(CHEBI:28115)
has role
cofactor
(CHEBI:23357)
molybdopterin cofactor
(CHEBI:25372)
has role
cofactor
(CHEBI:23357)
mycothiol
(CHEBI:16768)
has role
cofactor
(CHEBI:23357)
NAD(1−)
(CHEBI:57540)
has role
cofactor
(CHEBI:23357)
NAD+
(CHEBI:15846)
has role
cofactor
(CHEBI:23357)
NADH
(CHEBI:16908)
has role
cofactor
(CHEBI:23357)
NADH(2−)
(CHEBI:57945)
has role
cofactor
(CHEBI:23357)
NADP(3−)
(CHEBI:58349)
has role
cofactor
(CHEBI:23357)
NADP+
(CHEBI:18009)
has role
cofactor
(CHEBI:23357)
NADPH
(CHEBI:16474)
has role
cofactor
(CHEBI:23357)
NADPH(4−)
(CHEBI:57783)
has role
cofactor
(CHEBI:23357)
Ni(II)-pyridinium-3,5-bisthiocarboxylate mononucleotide(1−)
(CHEBI:137373)
has role
cofactor
(CHEBI:23357)
Ni(II)-pyridinium-3,5-bisthiocarboxylic acid mononucleotide
(CHEBI:137399)
has role
cofactor
(CHEBI:23357)
nickel cation
(CHEBI:25516)
has role
cofactor
(CHEBI:23357)
nickel(2+)
(CHEBI:49786)
has role
cofactor
(CHEBI:23357)
nicotinamide
(CHEBI:17154)
has role
cofactor
(CHEBI:23357)
NiFe4S4 cluster
(CHEBI:47739)
has role
cofactor
(CHEBI:23357)
NiFe4S5 cluster
(CHEBI:177874)
has role
cofactor
(CHEBI:23357)
pantetheine 4'-phosphate
(CHEBI:16858)
has role
cofactor
(CHEBI:23357)
pantetheine 4'-phosphate(2−)
(CHEBI:47942)
has role
cofactor
(CHEBI:23357)
pantothenic acids
(CHEBI:25848)
has role
cofactor
(CHEBI:23357)
phylloquinone
(CHEBI:18067)
has role
cofactor
(CHEBI:23357)
phytochromobilin
(CHEBI:26116)
has role
cofactor
(CHEBI:23357)
polypeptide-derived cofactor
(CHEBI:36079)
has role
cofactor
(CHEBI:23357)
porphyrins
(CHEBI:26214)
has role
cofactor
(CHEBI:23357)
potassium(1+)
(CHEBI:29103)
has role
cofactor
(CHEBI:23357)
premycofactocin
(CHEBI:150862)
has role
cofactor
(CHEBI:23357)
prenyl-FMN
(CHEBI:87749)
has role
cofactor
(CHEBI:23357)
prenyl-FMN(2−)
(CHEBI:87746)
has role
cofactor
(CHEBI:23357)
prenyl-FMNH2
(CHEBI:87531)
has role
cofactor
(CHEBI:23357)
pyridoxal
(CHEBI:17310)
has role
cofactor
(CHEBI:23357)
pyridoxal 5'-phosphate
(CHEBI:18405)
has role
cofactor
(CHEBI:23357)
pyridoxal 5'-phosphate(2−)
(CHEBI:597326)
has role
cofactor
(CHEBI:23357)
pyridoxal hydrochloride
(CHEBI:131529)
has role
cofactor
(CHEBI:23357)
pyridoxine
(CHEBI:16709)
has role
cofactor
(CHEBI:23357)
pyrroloquinoline cofactor
(CHEBI:26461)
has role
cofactor
(CHEBI:23357)
pyrroloquinoline quinone
(CHEBI:18315)
has role
cofactor
(CHEBI:23357)
pyrroloquinoline quinone(3−)
(CHEBI:58442)
has role
cofactor
(CHEBI:23357)
pyruvate
(CHEBI:15361)
has role
cofactor
(CHEBI:23357)
pyruvic acid
(CHEBI:32816)
has role
cofactor
(CHEBI:23357)
riboflavin
(CHEBI:17015)
has role
cofactor
(CHEBI:23357)
riboflavin(1−)
(CHEBI:57986)
has role
cofactor
(CHEBI:23357)
sapropterin
(CHEBI:59560)
has role
cofactor
(CHEBI:23357)
siroheme
(CHEBI:28599)
has role
cofactor
(CHEBI:23357)
siroheme(8−)
(CHEBI:60052)
has role
cofactor
(CHEBI:23357)
sirohydrochlorin
(CHEBI:18023)
has role
cofactor
(CHEBI:23357)
sirohydrochlorin(8−)
(CHEBI:58351)
has role
cofactor
(CHEBI:23357)
sodium(1+)
(CHEBI:29101)
has role
cofactor
(CHEBI:23357)
strontium(2+)
(CHEBI:35104)
has role
cofactor
(CHEBI:23357)
sulfate
(CHEBI:16189)
has role
cofactor
(CHEBI:23357)
tetra-μ3-sulfido-tetrairon
(CHEBI:49883)
has role
cofactor
(CHEBI:23357)
tetrahydromonapterin
(CHEBI:71177)
has role
cofactor
(CHEBI:23357)
thiamine(1+) diphosphate
(CHEBI:9532)
has role
cofactor
(CHEBI:23357)
thiamine(1+) diphosphate(3−)
(CHEBI:58937)
has role
cofactor
(CHEBI:23357)
vanadium cation
(CHEBI:35172)
has role
cofactor
(CHEBI:23357)
vitamin B6 phosphate
(CHEBI:36970)
has role
cofactor
(CHEBI:23357)
zeaxanthin
(CHEBI:27547)
has role
cofactor
(CHEBI:23357)
zinc(2+)
(CHEBI:29105)
has role
cofactor
(CHEBI:23357)
coenzyme
(CHEBI:23354)
is a
cofactor
(CHEBI:23357)
prosthetic group
(CHEBI:26348)
is a
cofactor
(CHEBI:23357)
siderophore
(CHEBI:26672)
is a
cofactor
(CHEBI:23357)
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