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Zbtb38 Gene Detail
Summary
  • Symbol
    Zbtb38
  • Name
    zinc finger and BTB domain containing 38
  • Synonyms
    A930014K01Rik, CIBZ, Zenon homolog
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442866
    NCBI Gene: 245007
  • Alliance
    gene page
  • Transcription Start Sites
    17 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:96564820-96613728 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 50.71 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1246 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442866
 protein coding gene Chr9:96564820-96634884 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035146
 protein coding gene Chr9:97895681-97969157 (-)
A/J MGP_AJ_G0035128
 protein coding gene Chr9:94470875-94541371 (-)
AKR/J MGP_AKRJ_G0035059
 protein coding gene Chr9:96776572-96848672 (-)
BALB/cJ MGP_BALBcJ_G0035120
 protein coding gene Chr9:94151919-94223987 (-)
C3H/HeJ MGP_C3HHeJ_G0034830
 protein coding gene Chr9:97179942-97250561 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035640
 protein coding gene Chr9:100712458-100787496 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032540
 protein coding gene Chr9:92302232-92373841 (-)
CAST/EiJ MGP_CASTEiJ_G0034142
 protein coding gene Chr9:96960039-97032202 (-)
CBA/J MGP_CBAJ_G0034798
 protein coding gene Chr9:104191229-104268132 (-)
DBA/2J MGP_DBA2J_G0034960
 protein coding gene Chr9:93990264-94061598 (-)
FVB/NJ MGP_FVBNJ_G0034908
 protein coding gene Chr9:92837897-92909255 (-)
LP/J MGP_LPJ_G0035039
 protein coding gene Chr9:98154312-98227408 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034947
 protein coding gene Chr9:106180347-106254632 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035662
 protein coding gene Chr9:97012643-97084693 (-)
PWK/PhJ MGP_PWKPhJ_G0033849
 protein coding gene Chr9:94171539-94243096 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033684
 protein coding gene Chr9:97062220-97136748 (-)
WSB/EiJ MGP_WSBEiJ_G0034262
 protein coding gene Chr9:96875695-96948211 (-)



Homology
more
  • Human Ortholog
    ZBTB38, zinc finger and BTB domain containing 38
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZBTB38, zinc finger and BTB domain containing 38
  • Synonyms
    CIBZ, PPP1R171, ZNF921
  • Links
    NCBI Gene ID: 253461
    neXtProt AC: NX_Q8NAP3
    UniProt: Q8NAP3

  • Chr Location
    3q23; chr3:141324186-141449792 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Mice homozygous for a null allele exhibit normal size. Mice homozygous for a conditional allele activated in hematopoietic cells exhibit normal hematopoietic cell development and B cell function.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    730
  • Tissues
    15
  • cDNA Data
    7
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 245007 NCBI Gene Model | MGI Sequence Detail 48909 C57BL/6J ±  kb
transcript NM_175537 RefSeq | MGI Sequence Detail 4091 Not Specified  
polypeptide NP_001346888 RefSeq | MGI Sequence Detail 1197 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:324629 Nishio M, et al., Heterozygous loss of Zbtb38 leads to early embryonic lethality via the suppression of Nanog and Sox2 expression. Cell Prolif. 2022 Apr;55(4):e13215
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory