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pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta [ Thunnus maccoyii (southern bluefin tuna) ]

Gene ID: 121895644, updated on 8-May-2024

Summary

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Gene symbol
pik3cd
Gene description
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
See related
EnsemblRapid:ENSTMYG00005009265
Gene type
protein coding
RefSeq status
MODEL
Organism
Thunnus maccoyii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Pelagiaria; Scombriformes; Scombridae; Thunnus
Orthologs
human zebrafish all
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Genomic context

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See pik3cd in Genome Data Viewer
Location:
chromosome: 4
Exon count:
24
Annotation release Status Assembly Chr Location
100 current fThuMac1.1 (GCF_910596095.1) 4 NC_056536.1 (14749077..14770553, complement)

Chromosome 4 - NC_056536.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121895793 Neighboring gene catenin, beta interacting protein 1 Neighboring gene transmembrane protein 201 Neighboring gene forkhead box L2-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056536.1 Chromosome 4 Reference fThuMac1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Thunnus maccoyii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fThuMac1.1 Primary Assembly

Genomic

  1. NC_056536.1 Reference fThuMac1.1 Primary Assembly

    Range
    14749077..14770553 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042409014.1 → XP_042264948.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X2

    Related
    ENSTMYP00005023945.1, ENSTMYT00005025666.1
    Conserved Domains (5) summary
    cd08693
    Location:315 → 482
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:506 → 675
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cl02483
    Location:36 → 108
    PI3K_p85B; PI3-kinase family, p85-binding domain
    cl02484
    Location:190 → 277
    PI3K_rbd; PI3-kinase family, ras-binding domain
    cl21453
    Location:677 → 1038
    PKc_like; Protein Kinases, catalytic domain

  2. XM_042409013.1 → XP_042264947.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    Related
    ENSTMYP00005023920.1, ENSTMYT00005025641.1
    Conserved Domains (5) summary
    cd08693
    Location:316 → 483
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:507 → 676
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cl02483
    Location:36 → 108
    PI3K_p85B; PI3-kinase family, p85-binding domain
    cl02484
    Location:190 → 277
    PI3K_rbd; PI3-kinase family, ras-binding domain
    cl21453
    Location:678 → 1039
    PKc_like; Protein Kinases, catalytic domain

  3. XM_042409015.1 → XP_042264949.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X3

    Conserved Domains (4) summary
    cd08693
    Location:174 → 341
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:365 → 534
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cl02484
    Location:48 → 135
    PI3K_rbd; PI3-kinase family, ras-binding domain
    cl21453
    Location:536 → 897
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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