Schistosomiasis in African infants and preschool children: let them now be treated!

Trends Parasitol. 2013 Apr;29(4):197-205. doi: 10.1016/j.pt.2013.02.001. Epub 2013 Mar 4.

Abstract

The occurrence of schistosomiasis within African infants and preschool children has been much better documented in recent years, revealing an important burden of disease previously overlooked. Despite mounting evidence showing that treatment with praziquantel is safe, beneficial, and could be delivered within ongoing public health interventions, young children still do not have satisfactory access to this drug, and a significant treatment gap exists. Progress towards resolution of this unfortunate health inequity is highlighted, including the development of an appropriate paediatric praziquantel formulation, and present blocks are identified on securing this issue within the international health agenda.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Africa / epidemiology
  • Animals
  • Anthelmintics / administration & dosage
  • Anthelmintics / pharmacokinetics
  • Anthelmintics / therapeutic use*
  • Child, Preschool
  • Humans
  • Infant
  • Praziquantel / administration & dosage
  • Praziquantel / pharmacokinetics
  • Praziquantel / therapeutic use*
  • Prevalence
  • Public Health
  • Schistosomiasis / drug therapy*
  • Schistosomiasis / epidemiology

Substances

  • Anthelmintics
  • Praziquantel