AmiGO 2: Term Details for "elongator holoenzyme complex" (GO:0033588)

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Term Information

Accession: GO:0033588
Name: elongator holoenzyme complex
Ontology: cellular_component
Synonyms: Elongator core complex
Alternate IDs: GO:0033589
Definition: A heterohexameric protein complex composed two discrete heterotrimeric subcomplexes that is involved in modification of wobble nucleosides in tRNA. Source: PMID:11689709, GOC:jh, PMID:15769872, PMID:11435442, PMID:18755837, PMID:23165209, GOC:vw, PMID:17018299, GOC:mah, GOC:bhm
Comment: Despite its name, this complex is not directly involved in transcriptional elongation (PMID:23165209).
History: See term history for GO:0033588 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to elongator holoenzyme complex (excluding "regulates").; Link to all direct and indirect annotations to elongator holoenzyme complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for elongator holoenzyme complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009058 biosynthetic process
GO:0008152 metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:0009987 cellular process
GO:0009059 macromolecule biosynthetic process
GO:0043170 macromolecule metabolic process
GO:0090304 nucleic acid metabolic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0044238 primary metabolic process
GO:0141187 nucleic acid biosynthetic process
GO:0016070 RNA metabolic process
GO:0010467 gene expression
GO:0032774 RNA biosynthetic process
GO:0043412 macromolecule modification
GO:0006396 RNA processing
GO:0006399 tRNA metabolic process
GO:0005575 cellular_component
GO:0003674 molecular_function
GO:0009451 RNA modification
GO:0008033 tRNA processing
GO:0003824 catalytic activity
GO:0032991 protein-containing complex
GO:0006400 tRNA modification
GO:1902494 catalytic complex
GO:0140535 intracellular protein-containing complex
GO:0002097 tRNA wobble base modification
GO:0033588 elongator holoenzyme complex

Parents of elongator holoenzyme complex (GO:0033588)

subject	relation	object
elongator holoenzyme complex	is_a	intracellular protein-containing complex (GO:0140535)
elongator holoenzyme complex	RO:0002216	tRNA wobble base modification (GO:0002097)
elongator holoenzyme complex	is_a	catalytic complex (GO:1902494)

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