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Free Microbiology Resources

CLSI Micro Free

M100, M23, M23 Supplements, M27M44S, and M45

Micro Free (formerly M100 Free) includes read-only access to critical microbiology standards. These standards are essential for better patient outcomes and reducing antimicrobial resistance. CLSI is committed to making resources broadly available to users around the globe to save lives and improve patient health.

CLSI VET01S

Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated From Animals

Quickly reference the most trusted AST veterinary breakpoint tables as a convenient, complimentary supplement to the AST VET01 document.

CLSI AST Rationale Documents

Package of Rationale Documents

Providing the scientific reasons behind breakpoint decisions.

CLSI Breakpoint Implementation Toolkit

Breakpoint Implementation Toolkit

Together CLSI, Association of Public Health Laboratories (APHL), American Society for Microbiology (ASM), College of American Pathologists (CAP), and Centers for Disease Control and Prevention (CDC), have jointly developed this Breakpoint Implementation Toolkit (BIT) to assist clinical laboratories in updating minimal inhibitory concentration (MIC) breakpoints.

Free Method Evaluation Resources

CLSI EP19

A Framework for Using CLSI Documents to Evaluate Medical Laboratory Test Methods, 3rd Edition

This report introduces the Test Life Phases Model, which points users to CLSI evaluation protocol documents to establish and implement commercially manufactured or laboratory-developed test methods.

CLSI EP36

Harmonization of Symbology and Equations, 1st Edition

This report provides a standardized symbology for use throughout CLSI documents.

COVID-19 Testing Resources

CLSI GP36

Planning for Laboratory Operations During a Disaster, 1st Edition

This document provides guidance for laboratory and health care leadership for development, implementation, and sustainment of effective emergency preparedness plans (all hazards) supporting nonanalytical components of clinical and public health laboratory services that may pertain to various natural and manmade disasters. 

CLSI MM14

Design of Molecular Proficiency Testing/External Quality Assessment, 2nd Edition

This document provides guidelines for a quality proficiency testing/external quality assessment program, including reliable databases; design control in the choice of materials and measurands; good manufacturing processes; documentation procedures; complaint handling; corrective and preventive action plans; and responsive timing of reports. 

CLSI POCT07

Quality Management: Approaches to Reducing Errors at the Point of Care, 1st Edition

This document presents the core infrastructure for a standardized error tracking system with the primary goals of reducing risk and increasing quality of point-of-care testing, while accumulating standardized data for benchmarking use. 

CLSI POCT18

Selection Process for CLIA-Waived Testing for SARS-CoV-2, Respiratory Syncytial Virus, and Influenza Viruses, 1st Edition

This white paper includes information related to selection considerations of CLIA-waived SARS-CoV-2, respiratory syncytial virus, and influenza virus testing.

Free COVID-19 Webinars

CLSI EP07 Free Overview Webinar

EP07 Overview: Interference Testing in Clinical Chemistry Webinar

CLSI EP17 Free Overview Webinar

EP17 Overview: Evaluation of Detection Capability for Clinical Laboratory Measurement Procedures Webinar

CLSI GP41 Free Overview Webinar

Collection of Diagnostic Venous Blood Specimens Webinar

CLSI M29 Free Overview Webinar

Protection of Laboratory Workers From Occupationally Acquired Infections Webinar

CLSI MM03 Free Overview Webinar

MM03 Overview: Molecular Diagnostic Methods for Infectious Diseases Webinar

CLSI Free: POCT for COVID-19 Testing

Best Practices for Point-of-Care Implementation of COVID-19 Testing Webinar

Best Practices for Point-of-Care Implementation of COVID-19 Testing

CLSI QMS03 Free Overview Webinar

Using QMS03, Training and Competence Assessment, On-Demand Webinar

Free Recent Webinars

CLSI MM09 Webinar

MM09: Modernizing Guidance for Clinical Sequencing: Human Genetic and Genomic Testing Using Traditional and High-Throughput Nucleic Acid Sequencing Methods Webinar

This webinar presents an overview of MM09: Human Genetic and Genomic Testing Using Traditional and High-Throughput Nucleic Acid Sequencing Methods, 3rd Edition.

CLSI On Demand - M47 Webinar

What's New in CLSI M47, Principles and Procedures for Blood Culture, 2nd Edition Webinar

Learn about the latest changes in CLSI's newly revised M47 document, Principles and Procedures for Blood Cultures, 2nd edition.