File:Cryptitis high mag.jpg

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English: High magnification micrograph of cryptitis in a case of Crohn's disease. H&E stain. Colonic biopsy of the mucosa.

The micrograph show numerous neutrophils within the crypt and several eosinophils. The findings in this image (alone) are not diagnostic for Crohn's disease.

The deep aspect of the biopsy has larger hyperchromatic, i.e. darker staining, nuclei, as is typical of the crypt base. The nuclei "mature", i.e. get smaller and less hyperchromatic, toward the superficial aspect; this is a normal finding, which is often absent in dysplastic lesions (e.g. tubular adenoma).

  • Intermed. mag.
    Intermed. mag.
  • High mag. view of crypt branching (feature of chronic colitis).
    High mag. view of crypt branching (feature of chronic colitis).
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Author Nephron
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current05:31, 8 December 2009Thumbnail for version as of 05:31, 8 December 20092,848 × 4,272 (4.29 MB)Nephron (talk | contribs){{Information |Description={{en|1=High magnification micrograph of '''cryptitis''' in a case of Crohn's disease. H&E stain. Colonic biopsy of the mucosa. The micrograph s

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