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5-Ethynyl-2′-deoxyuridine (EdU) is a thymidine analogue which is incorporated into the DNA of dividing cells. EdU is used to assay DNA synthesis in cell culture and detect cells in embryonic, neonatal and adult animals which have undergone DNA synthesis. Whilst at high doses it can be cytotoxic, this molecule is now widely used to track proliferating cells in multiple biological systems.

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  • 5-Ethynyl-2′-deoxyuridine (EdU) is a thymidine analogue which is incorporated into the DNA of dividing cells. EdU is used to assay DNA synthesis in cell culture and detect cells in embryonic, neonatal and adult animals which have undergone DNA synthesis. Whilst at high doses it can be cytotoxic, this molecule is now widely used to track proliferating cells in multiple biological systems. EdU-labelling allows cells to be isolated without denaturing RNA, allowing researchers to determine the transcriptional profile of cells. This approach has been used to assess transcription in neuronal cells and tissues that have recently divided either in vitro or in vivo. (en)
  • 5-乙炔基-2'-脱氧尿苷(英語:5-Ethynyl-2'-deoxyuridine,简称为EdU)是一种新型胸苷类似物,可掺入分裂中的细胞。较高剂量时会有细胞毒性。 (zh)
dbo:alternativeName
  • 2′-Deoxy-5-ethynyluridine; 5-Ethynyl-2′-deoxyuridine (en)
dbo:iupacName
  • 5-Ethynyl-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4(1H,3H)-dione (en)
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  • changed (en)
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  • 5-乙炔基-2'-脱氧尿苷(英語:5-Ethynyl-2'-deoxyuridine,简称为EdU)是一种新型胸苷类似物,可掺入分裂中的细胞。较高剂量时会有细胞毒性。 (zh)
  • 5-Ethynyl-2′-deoxyuridine (EdU) is a thymidine analogue which is incorporated into the DNA of dividing cells. EdU is used to assay DNA synthesis in cell culture and detect cells in embryonic, neonatal and adult animals which have undergone DNA synthesis. Whilst at high doses it can be cytotoxic, this molecule is now widely used to track proliferating cells in multiple biological systems. (en)
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  • 5-Ethynyl-2'-deoxyuridine (en)
  • 5-乙炔基-2'-脱氧尿苷 (zh)
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  • 5-Ethynyl-2′-deoxyuridine (en)
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