Issue 3, 2012
From the journal:

Natural Product Reports

Advances in Aspergillussecondary metabolite research in the post-genomic era

James F. Sanchez,a   Amber D. Somoza,b   Nancy P. Kellerc  and  Clay C. C. Wang*ab  

* Corresponding authors

a University of Southern California – Pharmacology and Pharmaceutical Sciences, Los Angeles, California, USA
E-mail: [email protected]
Fax: 001-323-442-1365
Tel: 001-323-442-1670

b University of Southern California – Chemistry, Los Angeles, California, USA

c University of Wisconsin, Madison – Medical Microbiology & Immunology and Bacteriology, Madison, Wisconsin, USA

Abstract

Covering: 2005 to 2011

This review studies the impact of whole genome sequencing on Aspergillus secondary metabolite research. There has been a proliferation of many new, intriguing discoveries since sequencing data became widely available. What is more, the genomes disclosed the surprising finding that there are many more secondary metabolite biosynthetic pathways than laboratory research had suggested. Activating these pathways has been met with some success, but many more dormant genes remain to be awakened.

Graphical abstract: Advances in Aspergillus secondary metabolite research in the post-genomic era

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/C2NP00084A
Article type
Review Article
Submitted
25 Oct 2011
First published
06 Jan 2012

Nat. Prod. Rep., 2012,29, 351-371

Permissions

Request permissions

Advances in Aspergillus secondary metabolite research in the post-genomic era

J. F. Sanchez, A. D. Somoza, N. P. Keller and C. C. C. Wang, Nat. Prod. Rep., 2012, 29, 351 DOI: 10.1039/C2NP00084A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements