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{{Redirect|E131|the Japanese train type|E131 series}}
{{Chembox
| Name = Patent Blue V
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<!-- Sections -->
|Section1={{Chembox Identifiers
| index1_label=Calcium salt
| Abbreviations =
| 3DMet =
| Beilstein =
| CASNo = 3536-49-0
| CASNo_Ref = {{cascite|correct|CAS}}
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 8QE473DV1Z
| CASNoOther =
| ChEBI = 59601
| ChemSpiderID = 69520
| SMILES = CCN(CC)c1ccc(cc1)C(=C2C=CC(=[N+](CC)CC)C=C2)c3cc(c(cc3S(=O)(=O)O)S(=O)(=O)O)O
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| StdInChIKey = DHAHKSQXIXFZJB-UHFFFAOYSA-O
| DrugBank =
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| Gmelin =
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| MeSHName =
| PubChem = 77074
| PubChem1 = 77073
| RTECS =
| UNNumber =
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| VaporPressure =
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| Section6 = {{Chembox Pharmacology
| ATCCode_prefix = V04
| ATCCode_suffix = CX09
}}
}}
'''Patent Blue V''', also called '''Food Blue 5''', '''Sulphan Blue''', Acid Blue 3, L-Blau 3, C-Blau 20, Patentblau V, Sky Blue, or C.I. 42051
==Use as dye==
[[File:E131 candies Auchan.jpg|thumb|left|Candies with Patent Blue V (E131) added]]
It is not widely used, but in Europe it can be found in [[Scotch egg]]s,{{cn|date=November 2017}} certain [[
In medicine, Patent Blue V is used in [[lymphangiography]] and [[sentinel node biopsy]] as a dye to color [[lymph vessel]]s.<ref>[http://jnm.snmjournals.org/cgi/content/full/44/4/649 Erratum - 44 (4): 649 - The Journal of Nuclear Medicine<!-- Bot generated title -->]</ref>
The color of the dye is [[pH]]-dependent. In aqueous solution, its color will vary from a deep blue in [[alkaline]] or weakly [[acidic]] medium to a yellow–orange in stronger acidic
conditions. It is useful as a [[pH indicator]] for the range 0.8–3.0.<ref>{{cite book |title= Handbook of Acid–Base Indicators |url= https://archive.org/details/handbookacidbase00sabn |url-access= limited |first= R. W. |last= Sabnis |publisher= CRC Press |year= 2008 |pages=
Because of its pH-dependent color, Patent Blue V was included in chemistry sets from [[Salter Science]] in the 1970s and 80s under the name ''Sky Blue''.
==Regulation==
Patent Blue V is banned as a [[food dye]] in [[Australia]] and [[US]], because health officials in these countries suspect that it may cause allergic reactions, with symptoms ranging from itching<ref name=Barthelmes2010>L. Barthelmes, A. Goyal, R.G. Newcombe, F. McNeill, R.E. Mansel,
==References==
{{Reflist}}
[[Category:Food colorings]]
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[[Category:Benzenesulfonic acids]]
[[Category:Anilines]]
[[Category:E-number additives]]
[[Category:Diethylamino compounds]]
[[Category:Acid dyes]]
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