Expressome: Difference between revisions
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'''Expressome''' may refer to: |
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'''Expressome''' refers to the whole set of [[gene expression]] in a [[Cell (biology)|cell]], tissue, organ, organisms, and species. |
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*A supramolecular complex consisting of RNA polymerase and a trailing ribosome linked by a shared mRNA. The expressome complex mediates a mechanism of gene expression regulation termed [[transcription-translation coupling]].<ref name="Kohler2017" /><ref name="Webster2020" /><ref name="OReilly2020" /> |
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Expressome is a slightly larger concept than [[transcriptome]]. |
*The whole set of [[gene expression]] in a [[Cell (biology)|cell]], tissue, organ, organisms, and species. Expressome is a slightly larger concept than [[transcriptome]]. The transcriptome is the set of transcripts, while expressome includes transcripts, [[protein]]s and other [[ligand]]s (abundance or concentration). |
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of transcripts, while expressome includes transcripts, [[protein]]s and other [[ligand]]s (how much |
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concentration). |
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==See also== |
==See also== |
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[[Category:Gene expression]] |
[[Category:Gene expression]] |
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==References== |
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{{Reflist|refs= |
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<ref name="Kohler2017">{{cite journal |author1=Kohler, R. |author2=Mooney, R. A. |author3=Mills, D. J. |author4=Landick, R. |author5=Cramer, P. |name-list-style=amp |year=2017 |title=Architecture of a transcribing-translating expressome. |journal=Science |volume=356 |issue=6334 |pages=194–197 |doi = 10.1126/science.aal3059 |pmid=28408604 |pmc=5528865 |bibcode=2017Sci...356..194K }}</ref> |
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<ref name="Webster2020">{{cite journal |author1=Webster, M. W. |author2=Takacs, M. |author3=Zhu, C.|author4=Vidmar, V. |author5=Eduljee, A. |author6=Abdelkareem, M. |author7=Weixlbaumer, A. |name-list-style=amp |year=2020 |title=Structural basis of transcription-translation coupling and collision in bacteria. |journal=Science |volume=369 |issue=6509 |pages=1355–1359 |doi = 10.1126/science.abb5036 |pmid=32820062 |bibcode=2020Sci...369.1355W |s2cid=221222557 |doi-access=free }}</ref> |
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<ref name="OReilly2020">{{cite journal |author1=O'Reilly, F. J. |author2=Xue, L. |author3=Graziadei, A.|author4=Sinn, L. |author5=Lenz, S. |author6=Tegunov, D. |author7=Blötz, C. |author8=Singh, N. |author9=Hagen, W. |author10=Cramer, P. |author11=Stülke, J. |author12=Mahamid, J. |author13=Rappsilber, J. |author13-link=Juri Rappsilber |name-list-style=amp |year=2020 |title=In-cell architecture of an actively transcribing-translating expressome. |journal=Science |volume=369 |issue=6503 |pages=554–557 |doi = 10.1126/science.abb3758 |pmid=32732422 |pmc=7115962 |bibcode=2020Sci...369..554O |hdl=21.11116/0000-0006-D30E-D |hdl-access=free }}</ref> |
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}} |
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{{genetics-stub}} |
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Latest revision as of 14:56, 29 January 2023
Expressome may refer to:
- A supramolecular complex consisting of RNA polymerase and a trailing ribosome linked by a shared mRNA. The expressome complex mediates a mechanism of gene expression regulation termed transcription-translation coupling.[1][2][3]
- The whole set of gene expression in a cell, tissue, organ, organisms, and species. Expressome is a slightly larger concept than transcriptome. The transcriptome is the set of transcripts, while expressome includes transcripts, proteins and other ligands (abundance or concentration).
See also
[edit]- Bioinformatics
- DNA microarray
- Gel electrophoresis
- Mass spectrometry
- Protein sequencing
- Systems biology
- Expressomics
- List of omics topics in biology
External links
[edit]References
[edit]- ^ Kohler, R.; Mooney, R. A.; Mills, D. J.; Landick, R. & Cramer, P. (2017). "Architecture of a transcribing-translating expressome". Science. 356 (6334): 194–197. Bibcode:2017Sci...356..194K. doi:10.1126/science.aal3059. PMC 5528865. PMID 28408604.
- ^ Webster, M. W.; Takacs, M.; Zhu, C.; Vidmar, V.; Eduljee, A.; Abdelkareem, M. & Weixlbaumer, A. (2020). "Structural basis of transcription-translation coupling and collision in bacteria". Science. 369 (6509): 1355–1359. Bibcode:2020Sci...369.1355W. doi:10.1126/science.abb5036. PMID 32820062. S2CID 221222557.
- ^ O'Reilly, F. J.; Xue, L.; Graziadei, A.; Sinn, L.; Lenz, S.; Tegunov, D.; Blötz, C.; Singh, N.; Hagen, W.; Cramer, P.; Stülke, J.; Mahamid, J. & Rappsilber, J. (2020). "In-cell architecture of an actively transcribing-translating expressome". Science. 369 (6503): 554–557. Bibcode:2020Sci...369..554O. doi:10.1126/science.abb3758. hdl:21.11116/0000-0006-D30E-D. PMC 7115962. PMID 32732422.
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