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== Preferred post-epipen medication? ==

To followup on a conversation that [[Talk:Anaphylaxis/Archive 1#contradiction with Benadryl / Diphenhydramine article|was archived]] while I was gone...

: The prefered post epi med? That depends on the situation. If you still have significant symptoms the prefered post epi med is more IM epi. And then if you are not better it is more IM epi again. And then if you are still not better one might move to iv epi or if you are on beta blockers glucagon. You can thrown in some diphenydramine, ranitidine, and steroids but are not to fool yourself that these at any time replace epi. At least that is my reading of the literature. [[User:Doc James|'''Doc James''']] ([[User talk:Doc James|talk]] · [[Special:Contributions/Doc James|contribs]] · [[Special:EmailUser/Doc James|email]]) 07:43, 2 August 2016 (UTC)

So I believe the advice I got in my "advanced remote areas first aid training" was that Benadryl would indeed *follow* administration of Epipen medication. I guess that correlates with the current statement in the Benadryl page:

: By injection it is often used in addition to [[epinephrine]] for [[anaphylaxis]].<ref name="Current EM">{{cite book | veditors = Humphries RL, Stone CK | title = CURRENT Diagnosis and Treatment Emergency Medicine, | edition = Seventh | series = LANGE CURRENT Series | publisher = McGraw–Hill Professional | location = | year = 2011 | pages = | isbn = 978-0-07-170107-5 | chapter = Chapter 11: Shock | vauthors = Young WF }}</ref> Its use for this purpose had not been properly studied {{Asof|2007|lc=y}}.<ref name=Cochrane2007rev>{{cite journal | vauthors = Sheikh A, ten Broek VM, Brown SG, Simons FE | title = H1-antihistamines for the treatment of anaphylaxis with and without shock | journal = The Cochrane Database of Systematic Reviews | issue = 1 | pages = CD006160 | date = January 2007 | pmid = 17253584 | doi = 10.1002/14651858.CD006160.pub2 }}</ref> Its use is only recommended once acute symptoms have improved.<ref name=AHSF2016>{{cite web|author1=American Society of Health-System Pharmacists|title=Diphenhydramine Hydrochloride|url=https://www.drugs.com/monograph/diphenhydramine-hydrochloride.html|website=Drugs.com|accessdate=2 August 2016|deadurl=no|archive-url=https://web.archive.org/web/20160915002404/https://www.drugs.com/monograph/diphenhydramine-hydrochloride.html|archivedate=15 September 2016|df=dmy-all}}</ref>

The situation(s) I am expecting (but obviously not hoping for) are when I travel in a remote area without access to proper medical facilities. IV, extra epi, any assistance is out of the question. The best case scenario is that the allergic person was smart enough to bring *one* epipen, but considering evacuation might take hours, I want to be able to keep the person stable in the long term. My understanding of the Epipen is that it lasts long enough to bring the patient to the hospital for further treatment, which is often impossible (in the short term) in the situations I end up with. My hope is that Benadryl pills might provide the necessary stabilization until we evacuate properly. But maybe that's naïve? In any case, I guess I should talk this over the counter with my pharmacist instead of asking Wikipedia. ;) Thanks for the references anyways, the drugs.com<ref name=AHSF2016/> and <ref name=Cochrane2007rev/> literature review are especially interesting: from what I understand, they "neither confirm nor deny" the practice, but it's still a commonly used pattern to treat severe allergic reactions... --[[User:TheAnarcat|TheAnarcat]] ([[User talk:TheAnarcat|talk]]) 20:34, 6 July 2019 (UTC)
::If one still has significant symptoms 5 min after a dose of epi, one gives more epi. [[User:Doc James|<span style="color:#0000f1">'''Doc James'''</span>]] ([[User talk:Doc James|talk]] · [[Special:Contributions/Doc James|contribs]] · [[Special:EmailUser/Doc James|email]]) 04:56, 7 July 2019 (UTC)


== Why was the boy's photo with Anaphylaxis removed? ==
== Inaccuracies in "Management" ==


I wanna know the reason for how the photo of that boy for the first thing you see in the article got removed, because I noticed it existed last time it was archived on https://archive.ph/d8Jru archived at 11 Jan 2024 23:38:56 UTC. [[User:Luigi Cotocea|Luigi Cotocea]] ([[User talk:Luigi Cotocea|talk]]) 10:08, 27 May 2024 (UTC)
Several allergy medications are described as being substitutes in beer. This is misleading and does not make sense.
:The image was [[:File:Angioedema2010.JPG]]. It was removed in [[Special:Diff/1223273998|this edit]] on 11 May 2024 by an IP address which has made no other edit. The reason given was "{{tq|Removal of angioedema which is not anaphylaxis. Angioedema is treated differently, has different pathophysiology and if linked with anaphylas could cause deaths. Get a picture of anaphylaxis rather than angioedema which is bradykinin induced when anaphylaxis is mast cell histamine induced.}}" That edit also removed [[angioedema]] from the infobox. The photo is present in that article. I don't know anything about the merits of the edit. [[User:Johnuniq|Johnuniq]] ([[User talk:Johnuniq|talk]]) 10:53, 27 May 2024 (UTC)
[[Special:Contributions/72.134.116.163|72.134.116.163]] ([[User talk:72.134.116.163|talk]]) 00:51, 2 September 2020 (UTC)
::I did some research. Apparently, angioedema is often treated with antihistamines or corticosteroids to reduce swelling, while anaphylaxis requires immediate epinephrine injection to counteract severe allergic reactions. Simple as that... [[User:Luigi Cotocea|Luigi Cotocea]] ([[User talk:Luigi Cotocea|talk]]) 15:19, 27 May 2024 (UTC)

Latest revision as of 15:19, 27 May 2024

Good articleAnaphylaxis has been listed as one of the Natural sciences good articles under the good article criteria. If you can improve it further, please do so. If it no longer meets these criteria, you can reassess it.
Article milestones
DateProcessResult
December 27, 2011Good article nomineeListed

Why was the boy's photo with Anaphylaxis removed?

[edit]

I wanna know the reason for how the photo of that boy for the first thing you see in the article got removed, because I noticed it existed last time it was archived on https://archive.ph/d8Jru archived at 11 Jan 2024 23:38:56 UTC. Luigi Cotocea (talk) 10:08, 27 May 2024 (UTC)[reply]

The image was File:Angioedema2010.JPG. It was removed in this edit on 11 May 2024 by an IP address which has made no other edit. The reason given was "Removal of angioedema which is not anaphylaxis. Angioedema is treated differently, has different pathophysiology and if linked with anaphylas could cause deaths. Get a picture of anaphylaxis rather than angioedema which is bradykinin induced when anaphylaxis is mast cell histamine induced." That edit also removed angioedema from the infobox. The photo is present in that article. I don't know anything about the merits of the edit. Johnuniq (talk) 10:53, 27 May 2024 (UTC)[reply]
I did some research. Apparently, angioedema is often treated with antihistamines or corticosteroids to reduce swelling, while anaphylaxis requires immediate epinephrine injection to counteract severe allergic reactions. Simple as that... Luigi Cotocea (talk) 15:19, 27 May 2024 (UTC)[reply]