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Andres M. Lozano

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Andres M. Lozano OC MD PhD FRCSC FRSC FCAHS FCNS is a Spanish-Canadian neurosurgeon and scientist known for his pioneering work in Deep Brain Stimulation and MR guided Focused Ultrasound Surgery. He holds the Alan & Susan Hudson Cornerstone Chair in Neurosurgery at the University Health Network and is a University Professor at the University of Toronto.

Early Life and Education

Andres Lozano was born in Sevilla, Spain, and moved to Canada at a young age. He completed his B.Sc in Cell Biology and his M.D. at the University of Ottawa in 1983. He then pursued a Ph.D. in Neurobiology at McGill University, graduating in 1989. Lozano completed his neurosurgical training, earning his FRCS(C) in 1990, and became a diplomate of the American Board of Neurological Surgery in 1994.

Career

Dr. Lozano’s career has been centered at the University of Toronto[1], where he has held several prestigious positions, including the Dan Family Chairman of Neurosurgery (2010-2020) and the RR Tasker Chair in Functional Neurosurgery (1999-2021). He has also been a Canadian Research Chair in Neuroscience and has contributed significantly to the field through his roles as an active staff member at the University Health Network since 1991.

Research and Contributions

Lozano is best known for his contributions to the development and application of Deep Brain Stimulation and Focused Ultrasound Surgery for various neurological disorders, including Parkinson’s disease, dystonia, depression, and Alzheimer’s disease. His research has resulted in over 830 publications, making him the most highly cited neurosurgeon globally according to Clarivate.

His team’s groundbreaking work has included the mapping of cortical and subcortical circuits and the development of novel therapies. Lozano has led numerous “first in man” trials, including DBS applications for conditions like Huntington’s disease and anorexia. His recent research has demonstrated that Deep Brain Stimulation can drive neurogenesis and enhance memory function.

Honors and Awards

Dr. Lozano’s contributions have been recognized through numerous awards and honors[2], including:

  • Named Canada Research Chair in Neurosciences 2005 and 2011
  • Elected to the Order of Spain 2007
  • Elected Fellow of the Royal Society of Canada 2009
  • Donald Calne International Award for Parkinson’s disease Research 2010
  • Winn Prize Award, 2010
  • Pioneer in Medicine Award, Society for Brain Mapping and Therapeutics, 2012
  • Elected Fellow of the Canadian Academy of Health Sciences, 2012
  • Olivecrona Medal, Karolinska Institute[3], 2012
  • Margolese National Brain Prize, University of British Columbia, 2013
  • Innovations Award, Canadian College of Neuropsychopharmacology, 2014
  • Named yearly from 2015-2022 Thomson Reuters Highly Cited Researchers and Most Influential Scientific Minds
  • Elected Fellow of the European Academy of Sciences 2016
  • Elected Officer of the Order of Canada 2016
  • TD Bank’s “10 Most Influential Hispanic Canadians” Award 2016
  • Doctor Honoris causa, University of Sevilla, Spain 2018
  • Lifetime Achievement Award, Faculty of Medicine, University of Ottawa, 2018
  • Named Honorary Member of the Colombian Society for Neurosurgery, 2019
  • Editor-in-Chief, Stereotactic and Functional Neurosurgery, 2020
  • Dandy Medal, Walter E. Dandy Society, 2021
  • SANS International Gold Medal, Saudi Association for Neurological Surgery, 2022
  • Honorary Member, Spanish Society for Neuromodulation, 2022
  • Norman Rosenblum Award for Excellence in Mentorship in the MD/PhD Program, University of Toronto, 2023
  • Fellow, International Association of Parkinsonism and Related Disorders, 2023
  • Named #2 in Canada on the Ranking of Best Neuroscientists in Canada (Research.com), 2023, 2024[4]
  • Inaugural Alim-Louis Benabid Award, Deep Brain Stimulation Society, 2024
  • Elected Fellow of the Congress of Neurological Surgeons, 2024

He has also been named one of Thomson Reuters’ Highly Cited Researchers program and Most Influential Scientific Minds annually from 2015 to 2022.

Editorial and Professional Roles

Lozano serves as the Editor-in-Chief of Stereotactic and Functional Neurosurgery[5]. He has been a founding member of several research organizations, including the Michael J. Fox Foundation and the Weston Foundation.

Selected Publications

Some of Dr. Lozano's most notable publications in recent years include:

  • “Deep Brain Stimulation: Current Challenges and Future Directions” (Nat Rev Neurol, 2019)[6]
  • “Cellular and Molecular Mechanisms of Action of Deep Brain Stimulation” (EMBO Mol Med, 2019)[7]
  • “Fornix-Region Deep Brain Stimulation Induced Memory Flashbacks in Alzheimer’s Disease” (N Engl J Med, 2019)[8]
  • “Trends and Disparities in Deep Brain Stimulation Utilization in the United States” (Lancet Reg Health Am, 2023)[9]


References

  1. ^ https://surgery.utoronto.ca/faculty-focus-andres-lozano. {{cite web}}: Missing or empty |title= (help)
  2. ^ https://medicineawards.utoronto.ca/2023-awards/winner/andres-lozano/. {{cite web}}: Missing or empty |title= (help)
  3. ^ https://www.olivecrona.eu/About. {{cite web}}: Missing or empty |title= (help)
  4. ^ https://research.com/u/andres-m-lozano. {{cite web}}: Missing or empty |title= (help)
  5. ^ https://karger.com/sfn/pages/editorial-board. {{cite web}}: Missing or empty |title= (help)
  6. ^ https://www.nature.com/articles/s41582-018-0128-2. {{cite web}}: Missing or empty |title= (help)
  7. ^ https://www.embopress.org/doi/full/10.15252/emmm.201809575#:~:text=Molecular%20effects%20of%20DBS%3A%20Inhibitory,the%20context%20of%20Parkinson's%20disease. {{cite web}}: Missing or empty |title= (help)
  8. ^ https://www.nejm.org/doi/full/10.1056/NEJMc1905240. {{cite web}}: Missing or empty |title= (help)
  9. ^ https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(23)00173-4/fulltext. {{cite web}}: Missing or empty |title= (help)