Expasy logo

ENZYME

ENZYME entry: EC 1.1.1.298

Accepted Name
3-hydroxypropionate dehydrogenase (NADP(+))
Alternative Name(s)
3-hydroxypropanoate dehydrogenase (NADP(+))
Reaction catalysed
3-hydroxypropanoate + NADP(+) = 3-oxopropanoate + H(+) + NADPH
Comment(s)
  • Catalyzes the reduction of 3-oxopropanoate to 3-hydroxypropanoate, a key step in the 3-hydroxypropanoate and the 3-hydroxypropanoate/4-hydroxybutyrate cycles, autotrophic CO2 fixation pathways found in some green non-sulfur phototrophic bacteria and archaea, respectively.
  • The enzyme from Chloroflexus aurantiacus is bifunctional, and also catalyzes the upstream reaction in the pathway, EC 1.2.1.75.
  • Different from EC 1.1.1.59 by cofactor preference.
Cross-references
BRENDA1.1.1.298
EC2PDB1.1.1.298
ExplorEnz1.1.1.298
PRIAM enzyme-specific profiles1.1.1.298
KEGG Ligand Database for Enzyme Nomenclature1.1.1.298
IUBMB Enzyme Nomenclature1.1.1.298
IntEnz1.1.1.298
MEDLINEFind literature relating to 1.1.1.298
MetaCyc1.1.1.298
Rhea expert-curated reactions1.1.1.298
UniProtKB/Swiss-Prot
A7MFX7, RUTE_CROS8A7ZKB3, RUTE_ECO24B7UNZ1, RUTE_ECO27
B7MIF5, RUTE_ECO45B7LFB8, RUTE_ECO55Q8XAU9, RUTE_ECO57
B5YU50, RUTE_ECO5EB7NLB8, RUTE_ECO7IB7MTF1, RUTE_ECO81
B7M8Z3, RUTE_ECO8AC4ZQD6, RUTE_ECOBWB1X9C9, RUTE_ECODH
A7ZYW3, RUTE_ECOHSA1A9R3, RUTE_ECOK1Q0TJ59, RUTE_ECOL5
Q8FJ44, RUTE_ECOL6B1IV89, RUTE_ECOLCP75894, RUTE_ECOLI
B7N3G4, RUTE_ECOLUB6I984, RUTE_ECOSEB1LIZ7, RUTE_ECOSM
Q1RDK9, RUTE_ECOUTA4W921, RUTE_ENT38B5XXN4, RUTE_KLEP3
A6T798, RUTE_KLEP7Q32HQ3, RUTE_SHIDSQ0T626, RUTE_SHIF8
Q83RV4, RUTE_SHIFLQ3Z3A5, RUTE_SHISSA1JMW8, RUTE_YERE8
Q8X505, YDFG_ECO57Q8FHD2, YDFG_ECOL6P39831, YDFG_ECOLI
P69935, YDFG_SALTIP69936, YDFG_SALTYQ83RE8, YDFG_SHIFL

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-