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SWEET - WWW-based rapid 3D construction of oligo- and polysaccharides.

Author information

Affiliations

  • 1. Deutsches Krebsforschungszentrum, Zentrale Spektroskopie, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.
      Authors
    • Bohne A 1
    (1 author)

Bioinformatics (Oxford, England), 01 Sep 1999, 15(9):767-768
https://doi.org/10.1093/bioinformatics/15.9.767 PMID: 10498779 

Abstract 

Unlabelled

SWEET is a WWW-based tool which rapidly converts the commonly used carbohydrate sequence information directly into a preliminary but reliable 3D model which can be visualised and written to files in several ways.

Availability

SWEET is accessible via the Internet at http://www.dkfz-heidelberg.de/spec/.

Contact

a. [email protected] or w.vonderlieth@ dkfz-heidelberg.de

Supplementary information

The current version of SWEET generates only one conformation out of a manifold. Several authors have analysed possible conformations of high-mannose N-linked glycans using a combination of NMR methods and computational approaches showing that such molecules are rather flexible populating normally several conformations for each glycosidic linkage. The displayed model exhibits for all glycosidic linkages a conformation which is in accordance with the reported variations of Phi, psi and omega values for specific linkage (see http://www.dkfz-heidelberg. de/spec/sweet2/doc/input/sba_example.html).

Full text links 

Read article at publisher's site: https://doi.org/10.1093/bioinformatics/15.9.767

Read article for free, from open access legal sources, via Unpaywall: https://academic.oup.com/bioinformatics/article-pdf/15/9/767/48835262/bioinformatics_15_9_767.pdfUnpaywall

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