The necessity for routine angiography in evaluation of the vasculature of recipient legs prior to microsurgical free-tissue reconstruction still remains controversial. This prospective study was designed to determine the indications and limitations of angiography pertinent to this issue. The protocol consisted of palpation of dorsalis pedis and posterior tibial artery pulsation and lower-limb angiography prior to surgery, as well as intraoperative observation of the posterior tibial, anterior tibial, and peroneal arteries. Thirty-six patients were included who were treated from November, 1993 to December 1998. In five patients either the posterior tibial pulse (1), the dorsalis pedis pulse (3), or both pedal pulses, including the popliteal pulse (1) were not palpable preoperatively. These clinical findings correlated with the vascular lesion images on angiography. In two patients, pedal pulse palpation could not clearly be evaluated because of the injury. Among the 29 patients with both pedal pulses palpable, three patients angiographically presented an injury of the peroneal artery, and one patient a pseudoaneurysm of the anterior tibial artery. In none of the cases with at least one palpable pedal pulse (33), did preoperative angiography add relevant information which led to a plan change in the free-flap transfer. However, in two cases, severe scarring and fibrosis required an intraoperative change of the recipient vessel in one case, and a change of the anastomosis level and use of a vein graft, in the other case, although the angiography had demonstrated normal vascularity in both. The authors conclude that preoperative angiography is indicated only when both pedal pulses are not palpable, and that normal preoperative angiography does not guarantee the presence of vessels suitable for anastomosis.