Chemical structure of E. coli lipid-A

Imoto

Tetrahedron Lett 1985

Preparation and antitumor activity of non-toxic lipid A

Ribi

Cancer Immunol Immunother 1982

Adjuvant and antitumour activities of synthetic lipid A analogues.

Ukei S, Iida J, Shiba T, Kusumoto S, Azuma I

Vaccine, (1):21-24 1986

MED: 3962449

Mechanisms of the antitumoral effect of lipid A.

Reisser D, Pance A, Jeannin JF

Bioessays, (3):284-289 2002

MED: 11891766

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4.

Shimazu R, Akashi S, Ogata H, Nagai Y, Fukudome K, Miyake K, Kimoto M

J Exp Med, (11):1777-1782 1999

MED: 10359581

Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-alpha) translation: glucocorticoids inhibit TNF-alpha translation by blocking JNK/SAPK.

Swantek JL, Cobb MH, Geppert TD

Mol Cell Biol, (11):6274-6282 1997

MED: 9343388

Cure of colon cancer metastasis in rats with the new lipid A OM 174. Apoptosis of tumor cells and immunization of rats.

Onier N, Hilpert S, Arnould L, Saint-Giorgio V, Davies JG, Jeannin JF, Jeannin JF

Clin Exp Metastasis, (4):299-306 1999

MED: 10545016

The adjuvant OM-174 induces both the migration and maturation of murine dendritic cells in vivo.

Pajak B, Garze V, Davies G, Bauer J, Moser M, Chiavaroli C

Vaccine, (9-10):836-842 2003

MED: 12547591

Combination treatment using thymosin alpha 1 and interferon after cyclophosphamide is able to cure Lewis lung carcinoma in mice.

Garaci E, Mastino A, Pica F, Favalli C

Cancer Immunol Immunother, (3):154-160 1990

MED: 2126987

Combination therapy with thymosin alpha 1 potentiates the anti-tumor activity of interleukin-2 with cyclophosphamide in the treatment of the Lewis lung carcinoma in mice.

Mastino A, Favalli C, Grelli S, Rasi G, Pica F, Goldstein AL, Garaci E

Int J Cancer, (3):493-499 1992

MED: 1735618