Europe PMC

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our privacy notice and cookie policy.

Tumor cell collagenase and its inhibition by a cartilage-derived protease inhibitor.

Science, 01 May 1977, 196(4290):653-654
https://doi.org/10.1126/science.193181 PMID: 193181 

Abstract 

Human osteosarcoma and mammary carcinoma cells were cultured separately in a medium supplemented with fetal calf serum, until they were confluent. The medium was then replaced by serum-free medium supplemented with heparin. Both cell cultures secreted collagenase, and this activity was inhibited by a cartilage-derived protein of low molecular weight. Since cartilage is rarely invaded by neoplasms, the presence of this inhibitor may play an important role in the regulation of tumor invasion.

Full text links 

Read article at publisher's site: https://doi.org/10.1126/science.193181

Citations & impact 

Impact metrics

70
Citations
Jump to Citations

Citations of article over time

Alternative metrics

Altmetric item for https://www.altmetric.com/details/41659673
Altmetric
Discover the attention surrounding your research
https://www.altmetric.com/details/41659673

Smart citations by scite.ai
Smart citations by scite.ai include citation statements extracted from the full text of the citing article. The number of the statements may be higher than the number of citations provided by EuropePMC if one paper cites another multiple times or lower if scite has not yet processed some of the citing articles.
Explore citation contexts and check if this article has been supported or disputed.
https://scite.ai/reports/10.1126/science.193181

Supporting
Mentioning
Contrasting
0
28
0

Article citations

Go to all (70) article citations

Similar Articles 

To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation.