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Transcriptional regulation and alternative splicing make for better brains.

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Affiliations

  • 1. Stem Cell and Brain Research Institute, Inserm U846, Bron, France.
      Authors
    • Dehay C 1
    (1 author)

ORCIDs linked to this article

Neuron, 01 May 2009, 62(4):455-457
https://doi.org/10.1016/j.neuron.2009.05.006 PMID: 19477147 

This is a comment on "Functional and evolutionary insights into human brain development through global transcriptome analysis." Neuron. 2009 May 28;62(4):494-509.

Abstract 

In this issue of Neuron, Johnson et al. employ a unique whole-genome exon-level analysis of the developing human brain showing that 76% of genes are expressed along with unexpectedly high levels of differential expression. These results have important consequences for understanding normal and pathological function and provide implications about the uniqueness of being human.

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Read article at publisher's site: https://doi.org/10.1016/j.neuron.2009.05.006

Read article for free, from open access legal sources, via Unpaywall: http://www.cell.com/article/S0896627309003572/pdfUnpaywall

HAL Open Archive
http://www.hal.inserm.fr/inserm-00409444

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