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Control of granulocytes and macrophages: molecular, cellular, and clinical aspects.

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Affiliations

  • 1. Walter and Eliza Hall Institute of Medical Research, Post Office Royal Melbourne Hospital, Victoria, Australia.
      Authors
    • Metcalf D 1
    (1 author)

Science, 01 Oct 1991, 254(5031):529-533
https://doi.org/10.1126/science.1948028 PMID: 1948028 

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Abstract 

The production and functional activity of two important white blood cells, the granulocytes and macrophages, are regulated mainly by a group of glycoprotein colony-stimulating factors. The colony-stimulating factors have been mass-produced with recombinant technology and are now proving of value in preventing or suppressing infections in a variety of individuals with subnormal or defective formation of blood cells.

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Read article at publisher's site: https://doi.org/10.1126/science.1948028

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