The Fisher variant of Guillain-Barré syndrome (Fisher syndrome).

Snyder LA; Rismondo V; Miller NR

doi:10.1097/wno.0b013e3181c2514b

Abstract

Fisher syndrome (FS) is an acute polyneuropathy typically characterized by the triad of ataxia, areflexia, and ophthalmoplegia, although it may present with 2 or even just 1 of these clinical findings. Similarities between FS and other acute polyneuropathies such as Guillain-Barré syndrome (GBS) and Bickerstaff brainstem encephalitis (BBE) suggest that FS is part of a spectrum of autoimmune disorders that may affect the peripheral and/or central nervous system. Anti-GQ1b antibody is present in the serum of more than 85% of patients with FS, but it is not specific to FS. Why some patients develop FS and others develop typical GBS or one of its other variants is still largely unknown.

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References

Articles referenced by this article (196)

Peripheral Neuritis. The Morrison Lectures, 1932, Delivered before the Royal College of Physicians of Edinburgh, May 1932.
Collier J
Edinb Med J, (10):601-618 1932
MED: 29639052
An unusual variant of acute idiopathic polyneuritis (syndrome of ophthalmoplegia, ataxia and areflexia).
FISHER M
N Engl J Med, (2):57-65 1956
MED: 13334797
Neuroanatomic evidence to explain why bilateral internuclear ophthalmoplegia may result from occlusion of a unilateral pontine branch artery.
Fisher CM
J Neuroophthalmol, (1):39-41 2004
MED: 15206438
Syndrome of external ophthalmoplegia, ataxia, and areflexia (Fisher); ocular manifestations in acute idiopathic polyneuritis (Guillain-Barre syndrome); report of two cases.
SMITH JL, WALSH FB
AMA Arch Ophthalmol, (1):109-114 1957
MED: 13434542
Bickerstaff's brainstem encephalitis: clinical features of 62 cases and a subgroup associated with Guillain-Barre syndrome.
Odaka M, Yuki N, Yamada M, Koga M, Takemi T, Hirata K, Kuwabara S
Brain, (Pt 10):2279-2290 2003
MED: 12847079
Diagnostic and classification criteria for the Guillain-Barre syndrome.
Van der Meche FG, Van Doorn PA, Meulstee J, Jennekens FG; GBS-consensus group of the Dutch Neuromuscular Research Support Centre
Eur Neurol, (3):133-139 2001
MED: 11306855
Serum IgG antibody to ganglioside GQ1b is a possible marker of Miller Fisher syndrome.
Chiba A, Kusunoki S, Shimizu T, Kanazawa I
Ann Neurol, (6):677-679 1992
MED: 1514781
Anti-GQ1b IgG antibody syndrome: clinical and immunological range.
Odaka M, Yuki N, Hirata K
J Neurol Neurosurg Psychiatry, (1):50-55 2001
MED: 11118247
Clinical and epidemiologic features of Guillain-Barre syndrome.
Hughes RA, Rees JH
J Infect Dis, S92-8 1997
MED: 9396689
Incidence and clinical features of acute inflammatory polyradiculoneuropathy in Lombardy, Italy, 1996.
Bogliun G, Beghi E; Italian GBS Registry Study Group
Acta Neurol Scand, (2):100-106 2004
MED: 15242417

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Miller-Fisher Syndrome Unveiled in the Presence of Cholangiocarcinoma.
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This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Miller Fisher Syndrome Associated With COVID-19: A History of Molecular Mimicry and an Up-to-Date Review of the Literature.
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Miller-Fisher syndrome with positive anti-GD1b and anti-GM1 antibodies combined with multiple autoimmune antibodies: A case report.
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Free full text in Europe PMC
Miller Fisher Syndrome Associated With COVID-19: A Child Case Report and an Up-to-Date Review of the Literature.
Poyraz T
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This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC

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Search life-sciences literature (45,103,589 articles, preprints and more)

The Fisher variant of Guillain-Barré syndrome (Fisher syndrome).

Affiliations

Authors

Abstract

Full text links

References

Peripheral Neuritis. The Morrison Lectures, 1932, Delivered before the Royal College of Physicians of Edinburgh, May 1932.

An unusual variant of acute idiopathic polyneuritis (syndrome of ophthalmoplegia, ataxia and areflexia).

Neuroanatomic evidence to explain why bilateral internuclear ophthalmoplegia may result from occlusion of a unilateral pontine branch artery.

Syndrome of external ophthalmoplegia, ataxia, and areflexia (Fisher); ocular manifestations in acute idiopathic polyneuritis (Guillain-Barre syndrome); report of two cases.

Bickerstaff's brainstem encephalitis: clinical features of 62 cases and a subgroup associated with Guillain-Barre syndrome.

Diagnostic and classification criteria for the Guillain-Barre syndrome.

Serum IgG antibody to ganglioside GQ1b is a possible marker of Miller Fisher syndrome.

Anti-GQ1b IgG antibody syndrome: clinical and immunological range.

Clinical and epidemiologic features of Guillain-Barre syndrome.

Incidence and clinical features of acute inflammatory polyradiculoneuropathy in Lombardy, Italy, 1996.

Citations & impact

Impact metrics

Citations of article over time

Alternative metrics

Article citations

Miller-Fisher Syndrome Unveiled in the Presence of Cholangiocarcinoma.

Clinical characteristics and prognosis of temporary miller fisher syndrome following COVID-19 vaccination: a systematic review of case studies.

Miller Fisher Syndrome Associated With COVID-19: A History of Molecular Mimicry and an Up-to-Date Review of the Literature.

Miller-Fisher syndrome with positive anti-GD1b and anti-GM1 antibodies combined with multiple autoimmune antibodies: A case report.

Miller Fisher Syndrome Associated With COVID-19: A Child Case Report and an Up-to-Date Review of the Literature.

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