Abstract
Background and aims
Recent studies suggest that calcium metabolism and perhaps other components of dairy products may contribute to shifting the energy balance and thus play a role in weight regulation. We compared the effects of cows' milk, calcium fortified soy milk and calcium supplement on weight and body fat reduction in premenopausal overweight and obese women.Methods and results
In this clinical trial, 100 healthy overweight or obese premenopausal women were randomized to one of the following dietary regimens for 8 weeks: (1) a control diet providing a 500kcal/day deficit, with 500-600mg/day dietary calcium; (2) a calcium-supplemented diet identical to the control diet with 800mg/day of calcium as calcium carbonate; (3) a milk diet providing a 500kcal/day deficit and containing three servings of low-fat milk; (4) a soy milk diet providing a 500kcal/day deficit and containing three servings of calcium fortified soy milk. At baseline and after 8 weeks, weight, waist circumference, and hip circumference were measured. Three 24-h dietary records and physical activity records were also taken. Comparing the mean differences in weight, waist circumference, body mass index (BMI) and waist-to-hip ratio (WHR) using repeated measure of variance analysis showed that changes in waist circumference and WHR were significant among the four groups (p=0.029 and p=0.015, respectively). After adjustment for baseline values, changes in weight and BMI were also significant (p=0.017 and p=0.019, respectively). Weight reductions in high milk, soy milk, calcium supplement and control groups were 4.43±1.93(kg), 3.46±1.28(kg), 3.89±2.40(kg) and 2.87±1.55(kg), respectively. The greatest changes were seen in the high dairy group in all variables.Conclusion
Increasing low fat milk consumption significantly reduces the general and central obesity beyond a low calorie diet.References
Articles referenced by this article (32)
Dietary calcium, obesity and hypertension--the end of the road?
J Clin Endocrinol Metab, (7):4411-4413 2005
MED: 16002411
Effects of moderate variations in macronutrient composition on weight loss and reduction in cardiovascular disease risk in obese, insulin-resistant adults.
Am J Clin Nutr, (4):813-821 2006
MED: 17023708
Effect of weight loss with or without orlistat treatment on adipocytokines, inflammation, and oxidative markers in obese women.
Hormones (Athens), (4):259-269 2006
MED: 17178701
[Effects of greater-than-5% weight reduction on hemodynamic, metabolic and neuroendocrine profiles of grade I obese subjects].
Arq Bras Cardiol, (1):12-21 2006
MED: 16906265
Association of hypoadiponectinemia with coronary artery disease in men.
Arterioscler Thromb Vasc Biol, (1):85-89 2003
MED: 12524229
Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia
J Clin Endocrinol Metab, (5) 2001
Weight reduction and cardiovascular and metabolic disease prevention: clinical trial update
J Am Coll Cardiol, (12) 2007
Calcium and dairy acceleration of weight and fat loss during energy restriction in obese adults.
Obes Res, (4):582-590 2004
MED: 15090625
Calcium intake and adiposity
Am J Clin Nutr 2003
Show 10 more references (10 of 32)
Citations & impact
Impact metrics
Citations of article over time
Alternative metrics
Smart citations by scite.ai
Explore citation contexts and check if this article has been
supported or disputed.
https://scite.ai/reports/10.1016/j.numecd.2009.11.013
Article citations
Impacts of dietary animal and plant protein on weight and glycemic control in health, obesity and type 2 diabetes: friend or foe?
Front Endocrinol (Lausanne), 15:1412182, 31 Jul 2024
Cited by: 0 articles | PMID: 39145315 | PMCID: PMC11321983
Review Free full text in Europe PMC
Milk protein concentrate supplementation improved appetite, metabolic parameters, adipocytokines, and body composition in dieting women with obesity: a randomized controlled trial.
BMC Nutr, 10(1):80, 03 Jun 2024
Cited by: 0 articles | PMID: 38831442 | PMCID: PMC11149337
Calcium supplementation for people with overweight or obesity.
Cochrane Database Syst Rev, 5:CD012268, 09 May 2024
Cited by: 0 articles | PMID: 38721870
Review
Is diet related to osteoarthritis? A univariable and multivariable Mendelian randomization study that investigates 45 dietary habits and osteoarthritis.
Front Nutr, 10:1278079, 16 Nov 2023
Cited by: 2 articles | PMID: 38035348 | PMCID: PMC10687195
Can the Substitution of Milk with Plant-Based Drinks Affect Health-Related Markers? A Systematic Review of Human Intervention Studies in Adults.
Nutrients, 15(11):2603, 01 Jun 2023
Cited by: 2 articles | PMID: 37299566 | PMCID: PMC10255899
Review Free full text in Europe PMC
Go to all (43) article citations
Similar Articles
To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation.
Effect of soy drink replacement in a weight reducing diet on anthropometric values and blood pressure among overweight and obese female youths.
Asia Pac J Clin Nutr, 20(3):383-389, 01 Jan 2011
Cited by: 17 articles | PMID: 21859656
Preliminary study: soy milk as effective as skim milk in promoting weight loss.
J Am Diet Assoc, 107(10):1811-1814, 01 Oct 2007
Cited by: 14 articles | PMID: 17904943
Calcium and dairy product modulation of lipid utilization and energy expenditure.
Obesity (Silver Spring), 16(7):1566-1572, 17 Apr 2008
Cited by: 54 articles | PMID: 18421269
Meta-analysis of studies of a specific delivery mode for a modified-carbohydrate diet.
J Hum Nutr Diet, 24(6):525-535, 07 Sep 2011
Cited by: 6 articles | PMID: 21899599
Review
Funding
Funders who supported this work.