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Biology and pathogenesis of chikungunya virus.

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  • 1. Institut Pasteur, 28 rue du Dr Roux, Paris 75724 Cedex 15, France.
      Authors
    • Schwartz O 1
    (1 author)

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Nature reviews. Microbiology, 01 Jul 2010, 8(7):491-500
https://doi.org/10.1038/nrmicro2368 PMID: 20551973 

Review

Abstract 

Chikungunya virus (CHIKV) is a re-emerging mosquito-borne alphavirus responsible for a recent, unexpectedly severe epidemic in countries of the Indian Ocean region. Although many alphaviruses have been well studied, little was known about the biology and pathogenesis of CHIKV at the time of the 2005 outbreak. Over the past 5 years there has been a multidisciplinary effort aimed at deciphering the clinical, physiopathological, immunological and virological features of CHIKV infection. This Review highlights some of the most recent advances in our understanding of the biology of CHIKV and its interactions with the host.

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Read article at publisher's site: https://doi.org/10.1038/nrmicro2368

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