Europe PMC

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our privacy notice and cookie policy.

Photodynamic therapy: mechanism of action and role in the treatment of skin disease.

Author information

Affiliations

  • 1. Department of Radiation Oncology, The Brody School of Medicine at East Carolina University, Greenville, NC 27834, USA.
      Authors
    • Allison RR 1
    (1 author)

Giornale Italiano di Dermatologia e Venereologia : Organo Ufficiale, Societa Italiana di Dermatologia e Sifilografia, 01 Aug 2010, 145(4):491-507
PMID: 20823792 

Review

Abstract 

The combination of lesion ablation with excellence in cosmetic outcome has allowed photodynamic therapy (PDT) an ever increasing role in the treatment of diseases of the skin. As currently practiced, PDT employs a photosensitizing agent that when activated by light energy creates a photodynamic reaction that is cytotoxic and vasculotoxic. The relative simplicity of therapy with its ability to achieve high response rates has brought PDT to a worldwide audience not only for oncologic indications but far more commonly to non oncologic indications. This paper will review the mechanism of action for PDT and highlight the versatile clinical outcomes reported from the peer reviewed literature.

Citations & impact 

Impact metrics

8
Citations
Jump to Citations

Citations of article over time

Article citations

Go to all (8) article citations

Similar Articles 

To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation.