Improving the efficacy of antibody-based cancer therapies.

Carter P

Nat Rev Cancer, (2):118-129 2001

MED: 11905803

Effects of drug loading on the antitumor activity of a monoclonal antibody drug conjugate.

Hamblett KJ, Senter PD, Chace DF, Sun MM, Lenox J, Cerveny CG, Kissler KM, Bernhardt SX, Kopcha AK, Zabinski RF, Meyer DL, Francisco JA

Clin Cancer Res, (20):7063-7070 2004

MED: 15501986

Advances in the production of human therapeutic proteins in yeasts and filamentous fungi.

Gerngross TU

Nat Biotechnol, (11):1409-1414 2004

MED: 15529166

Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index.

Junutula JR, Raab H, Clark S, Bhakta S, Leipold DD, Weir S, Chen Y, Simpson M, Tsai SP, Dennis MS, Lu Y, Meng YG, Ng C, Yang J, Lee CC, Duenas E, Gorrell J, Katta V, Kim A, [...] Mallet W

Nat Biotechnol, (8):925-932 2008

MED: 18641636

Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag.

Wu P, Shui W, Carlson BL, Hu N, Rabuka D, Lee J, Bertozzi CR

Proc Natl Acad Sci U S A, (9):3000-3005 2009

MED: 19202059

Title not supplied

Peters

Angew. Chem. 2010

Enzymatic site-specific functionalization of protein methyltransferase substrates with alkynes for click labeling.

Peters W, Willnow S, Duisken M, Kleine H, Macherey T, Duncan KE, Litchfield DW, Luscher B, Weinhold E

Angew Chem Int Ed Engl, (30):5170-5173 2010

MED: 20572224

Transglutaminases: crosslinking enzymes with pleiotropic functions.

Lorand L, Graham RM

Nat Rev Mol Cell Biol, (2):140-156 2003

MED: 12563291

Site-specific modification and PEGylation of pharmaceutical proteins mediated by transglutaminase.

Fontana A, Spolaore B, Mero A, Veronese FM

Adv Drug Deliv Rev, (1):13-28 2007

MED: 17916398

Single amino acid chelates (SAAC): a strategy for the design of technetium and rhenium radiopharmaceuticals.

Bartholoma M, Valliant J, Maresca KP, Babich J, Zubieta J

Chem Commun (Camb), (5):493-512 2008

MED: 19283279