The association between overcommitment to work and depressive symptoms is moderated by the polymorphic region of the 5-HTT gene.

Wirtz PH; Siegrist J; Schuhmacher A; Hoefels S; Maier W; Domes G; Schwab S; Zobel AW

doi:10.1016/j.psychres.2013.01.028

The association between overcommitment to work and depressive symptoms is moderated by the polymorphic region of the 5-HTT gene.

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Psychiatry Research, 22 Feb 2013, 208(2):199-200
https://doi.org/10.1016/j.psychres.2013.01.028 PMID: 23462387

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References

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Elevated brain serotonin turnover in patients with depression: effect of genotype and therapy.
Barton DA, Esler MD, Dawood T, Lambert EA, Haikerwal D, Brenchley C, Socratous F, Hastings J, Guo L, Wiesner G, Kaye DM, Bayles R, Schlaich MP, Lambert GW
Arch Gen Psychiatry, (1):38-46 2008
MED: 18180427
From inflammation to sickness and depression: when the immune system subjugates the brain.
Dantzer R, O'Connor JC, Freund GG, Johnson RW, Kelley KW
Nat Rev Neurosci, (1):46-56 2008
MED: 18073775
Effort-reward imbalance model and self-reported health: cross-sectional and prospective findings from the GAZEL cohort.
Niedhammer I, Tek ML, Starke D, Siegrist J
Soc Sci Med, (8):1531-1541 2004
MED: 14759696
Effect of a triallelic functional polymorphism of the serotonin-transporter-linked promoter region on expression of serotonin transporter in the human brain.
Parsey RV, Hastings RS, Oquendo MA, Hu X, Goldman D, Huang YY, Simpson N, Arcement J, Huang Y, Ogden RT, Van Heertum RL, Arango V, Mann JJ
Am J Psychiatry, (1):48-51 2006
MED: 16390888
The measurement of effort-reward imbalance at work: European comparisons.
Siegrist J, Starke D, Chandola T, Godin I, Marmot M, Niedhammer I, Peter R
Soc Sci Med, (8):1483-1499 2004
MED: 14759692

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Age-related associations between work over-commitment and zest for work among Swedish employees from a cross-sectional and longitudinal perspective.
Runeson-Broberg R, du Prel JB, Westerholm P, Nordin M, Knutsson A, Alfredsson L, Fahlén G, Peter R
Work, 57(2):269-279, 01 Jan 2017
Cited by: 2 articles | PMID: 28582947

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Solute carrier family 6 member 4(UniProt - B3VRQ0)
Solute carrier family 6 member 4(UniProt - B3VRU5)
Solute carrier family 6 member 4(UniProt - B3VRQ5)
Solute carrier family 6 member 4(UniProt - B3VRR0)
Solute carrier family 6 member 4(UniProt - B3VRS0)

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The association between overcommitment to work and depressive symptoms is moderated by the polymorphic region of the 5-HTT gene.

ORCIDs linked to this article

Abstract

Full text links

References

Elevated brain serotonin turnover in patients with depression: effect of genotype and therapy.

From inflammation to sickness and depression: when the immune system subjugates the brain.

Effort-reward imbalance model and self-reported health: cross-sectional and prospective findings from the GAZEL cohort.

Effect of a triallelic functional polymorphism of the serotonin-transporter-linked promoter region on expression of serotonin transporter in the human brain.

The measurement of effort-reward imbalance at work: European comparisons.

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Age-related associations between work over-commitment and zest for work among Swedish employees from a cross-sectional and longitudinal perspective.

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The association between overcommitment to work and depressive symptoms is moderated by the polymorphic region of the 5-HTT gene.

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