Europe PMC

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our privacy notice and cookie policy.

Radiometals: towards a new success story in nuclear imaging?

Author information

Affiliations

  • 1. Université de Strasbourg, IPHC, 23 rue du Loess, 67037 Strasbourg, France.
      Authors
    • Brasse D 1
    (1 author)

Dalton Transactions (Cambridge, England : 2003), 01 Mar 2015, 44(11):4845-4858
https://doi.org/10.1039/c4dt02911a PMID: 25437643 

Review

Abstract 

Several limitations of (18)F and other non-metallic isotopes have been emphasized by the development of macromolecular biotargeting agents for cancer, including peptides, antibodies, fragments and oligonucleotides, which typically have biological half-lives that are much longer than the radioactive half-life of (18)F. Based on the (18)F-FDG success story, we can wonder whether all critical criteria are or can be fulfilled for the radiometallated bioconjugates to start out from the crowd and which metals have the best chance of success. In this paper we give a brief overview of radiometal isotopes having the potential for PET imaging in terms of physical properties, production capacity and associated chemistry.

Full text links 

Read article at publisher's site: https://doi.org/10.1039/c4dt02911a

References 

Articles referenced by this article (153)

Show 10 more references (10 of 153)

Citations & impact 

Impact metrics

22
Citations
Jump to Citations

Citations of article over time

Alternative metrics

Altmetric item for https://www.altmetric.com/details/2850250
Altmetric
Discover the attention surrounding your research
https://www.altmetric.com/details/2850250

Article citations

Go to all (22) article citations

Similar Articles 

To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation.