Abstract
Purpose of review
Normal testicular descent is now recognized to occur in two steps with the first, transabdominal stage controlled by insulin-like hormone 3. The second, inguinoscrotal stage is controlled by androgens, mostly indirectly via the genitofemoral nerve, which appears to direct the migration of the gubernaculum to the scrotum. Undescended testis (UDT) is multifactorial, with only some of the genes identified. This review highlights recent developments that are leading to changes in practice.Recent findings
There is an emerging consensus among pediatric surgeons and urologists about the management of UDT with recommendations that the diagnosis of congenital UDT should be confirmed at 3-6 months of age and orchidopexy done at 6-12 months of age. With the recommendations for early surgery, recent studies focus on the complications of orchidopexy, to determine whether this is higher in infants than older children. In addition, there is general acceptance of the existence of 'acquired' UDT, which develops after about 2 years of age, but treatment for this group remains controversial.Summary
Evaluation of children with UDT now needs to be separated into the assessment of possible congenital UDT in infants at 0-6 months, for orchidopexy before 12 months, and preschool boys, who may be developing acquired UDT.Citations & impact
Impact metrics
Citations of article over time
Article citations
Diagnoses and Treatment of Acquired Undescended Testes: A Review.
Medicine (Baltimore), 103(27):e38812, 01 Jul 2024
Cited by: 0 articles | PMID: 38968470 | PMCID: PMC11224853
Review Free full text in Europe PMC
The Time of Diagnosis and Surgical Treatment of Congenital Cryptorchidism: A Single Center's Observational Study in Greece.
Cureus, 16(1):e51580, 03 Jan 2024
Cited by: 0 articles | PMID: 38313896 | PMCID: PMC10836180
Epididymal disjunction anomalies in undescended testis - a factor associated with spermatic obstruction.
Int Braz J Urol, 48(2):336-346, 01 Mar 2022
Cited by: 2 articles | PMID: 35170897 | PMCID: PMC8932036
Comparison of diagnostic and treatment guidelines for undescended testis.
Clin Exp Pediatr, 63(11):415-421, 23 Mar 2020
Cited by: 11 articles | PMID: 32252147 | PMCID: PMC7642136
Review Free full text in Europe PMC
Maternal smoking during pregnancy and risk of cryptorchidism: a systematic review and meta-analysis.
Eur J Pediatr, 178(3):287-297, 21 Nov 2018
Cited by: 11 articles | PMID: 30465272
Review
Go to all (9) article citations
Similar Articles
To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation.
Undescended testis: What paediatricians need to know.
J Paediatr Child Health, 53(11):1101-1104, 01 Nov 2017
Cited by: 16 articles | PMID: 29148186
Review
Natural history and long-term testicular growth of acquired undescended testis after spontaneous descent or pubertal orchidopexy.
BJU Int, 106(7):1052-1059, 11 Feb 2010
Cited by: 9 articles | PMID: 20151964
Perioperative surgical findings in congenital and acquired undescended testis.
J Pediatr Surg, 45(9):1874-1881, 01 Sep 2010
Cited by: 11 articles | PMID: 20850635
Cryptorchidism and Hypospadias
MDText.com, Inc., South Dartmouth (MA), 24 Apr 2015
Cited by: 0 articles | PMID: 25905331
ReviewBooks & documents Free full text in Europe PMC