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Regeneration of sensory hair cells after acoustic trauma.

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Affiliations

  • 1. Department of Zoology, University of Hawaii, Honolulu 96822.
      Authors
    • Corwin JT 1
    (1 author)

ORCIDs linked to this article

Science, 01 Jun 1988, 240(4860):1772-1774
https://doi.org/10.1126/science.3381100 PMID: 3381100 

Abstract 

Any loss of cochlear hair cells has been presumed to result in a permanent hearing deficit because the production of these cells normally ceases before birth. However, after acoustic trauma, injured sensory cells in the mature cochlea of the chicken are replaced. New cells appear to be produced by mitosis of supporting cells that survive at the lesion site and do not divide in the absence of trauma. This trauma-induced division of normally postmitotic cells may lead to recovery from profound hearing loss.

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Read article at publisher's site: https://doi.org/10.1126/science.3381100

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Funding 

Funders who supported this work.

NCRR NIH HHS (1)

NINDS NIH HHS (1)