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Mediterranean spotted fever: clinical, laboratory and epidemiological features of 199 cases.

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The American Journal of Tropical Medicine and Hygiene, 01 Jul 1986, 35(4):845-850
https://doi.org/10.4269/ajtmh.1986.35.845 PMID: 3728799 

Abstract 

Most previous studies of Mediterranean spotted fever (MSF) have included cases that either were not laboratory-confirmed or were confirmed by the Weil-Felix test. The authors report the detailed clinical, laboratory and epidemiological features of 199 serologically-confirmed cases of MSF (by microimmunofluorescence). This work demonstrates that the disease is difficult to diagnose, especially at the beginning; that it can be fatal (2.5% of cases); and that a rapid and specific diagnosis is necessary to identify atypical cases. Epidemiological features such as season (summer essentially), presence of a dog, and travel in an endemic area (the Mediterranean Basin) are important in the diagnosis. In such cases fever associated with rash have to be considered and treated as MSF.

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Read article at publisher's site: https://doi.org/10.4269/ajtmh.1986.35.845

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