Europe PMC

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our privacy notice and cookie policy.

Introduction to stem cells.

Author information

Affiliations

  • 1. State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, P.R. China.
      Authors
    • Tian Z 1
    • Yu T 1
    • Liu J 1
    • Wang T 1
    (4 authors)
  • 2. State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, P.R. China; Department of Chemical and Materials Engineering, National Central University, Jhongli, Taoyuan, Taiwan.
      Authors
    • Higuchi A 2
    (1 author)

Progress in Molecular Biology and Translational Science, 15 Mar 2023, 199:3-32
https://doi.org/10.1016/bs.pmbts.2023.02.012 PMID: 37678976 

Review

Abstract 

Stem cells have self-renewal capability and can proliferate and differentiate into a variety of functionally active cells that can serve in various tissues and organs. This review discusses the history, definition, and classification of stem cells. Human pluripotent stem cells (hPSCs) mainly include embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs). Embryonic stem cells are derived from the inner cell mass of the embryo. Induced pluripotent stem cells are derived from reprogramming somatic cells. Pluripotent stem cells have the ability to differentiate into cells derived from all three germ layers (endoderm, mesoderm, and ectoderm). Adult stem cells can be multipotent or unipotent and can produce tissue-specific terminally differentiated cells. Stem cells can be used in cell therapy to replace and regenerate damaged tissues or organs.

Full text links 

Read article at publisher's site: https://doi.org/10.1016/bs.pmbts.2023.02.012

Citations & impact 

Impact metrics

5
Citations
Jump to Citations

Citations of article over time

Article citations

Similar Articles 

To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation.