Europe PMC

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our privacy notice and cookie policy.

Association between anesthesia technique and death after hip fracture repair for patients with COVID-19.

Author information

Affiliations

  • 1. Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada.
      Authors
    • Nourouzpour N 1, 2
    • Ho CM 1
    (2 authors)
  • 2. Department of Anesthesiology, Pharmacology & Therapeutics, The University of British Columbia, Vancouver, BC, Canada.
      Authors
    • Nourouzpour N 1, 2
    • Jen TTH 2
    • Prabhakar C 2
    • Ke JXC 2, 3
    (4 authors)
  • 3. Department of Anesthesiology, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax, NS, Canada.
      Authors
    • Bailey J 3
    • Ke JXC 2, 3
    (2 authors)
  • 4. Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA.
      Authors
    • Jobin PG 4
    (1 author)
  • 5. Centre for Health Services and Policy Research, School of Population and Public Health, The University of British Columbia, Vancouver, BC, Canada.
      Authors
    • Sutherland JM 5
    (1 author)

ORCIDs linked to this article

Canadian Journal of Anaesthesia = Journal Canadien D'anesthesie, 21 Dec 2023, 71(3):367-377
https://doi.org/10.1007/s12630-023-02673-2 PMID: 38129357 

Abstract 

Purpose

Patients with COVID-19 undergoing hip fracture surgeries have a 30-day mortality of up to 34%. We aimed to evaluate the association between anesthesia technique and 30-day mortality after hip fracture surgery in patients with COVID-19.

Methods

After ethics approval, we performed a retrospective cohort analysis of the American College of Surgeons National Surgical Quality Improvement Program data set from January to December 2021. Inclusion criteria were age ≥ 19 yr, laboratory-confirmed SARS-CoV-2 infection within 14 days preoperatively, and hip fracture surgery under general anesthesia (GA) or spinal anesthesia (SA). Exclusion criteria were American Society of Anesthesiologists Physical Status V, ventilator dependence, international normalized ratio ≥ 1.5, partial thromboplastin time > 35 sec, and platelet count < 80 × 109 L-1. The primary outcome was all-cause 30-day mortality. The adjusted association between anesthetic technique and 30-day mortality was analyzed using multivariable logistic regression.

Results

Of 23,045 patients undergoing hip fracture surgery, 331 patients met the study criteria. The median [interquartile range] age was 82 [74-88] yr, and 32.3% were male. The 30-day mortality rate was 10.0% (33/331) for the cohort (10.7%, 29/272 for GA vs 6.8%, 4/59 for SA; P = 0.51; standardized mean difference, 0.138). The use of SA, compared with GA, was not associated with decreased mortality (adjusted odds ratio, 0.61; 95% confidence interval, 0.21 to 1.8; E-value, 2.49).

Conclusion

Anesthesia technique was not associated with mortality in patients with COVID-19 undergoing hip fracture surgery. The findings were limited by a small sample size.

Study registration

www.

Clinicaltrials

gov (NCT05133648); registered 24 November 2021.

Full text links 

Read article at publisher's site: https://doi.org/10.1007/s12630-023-02673-2

References 

Articles referenced by this article (35)

Show 10 more references (10 of 35)

Citations & impact 

Impact metrics

1
Citation
Jump to Citations

Alternative metrics

Altmetric item for https://www.altmetric.com/details/158506435
Altmetric
Discover the attention surrounding your research
https://www.altmetric.com/details/158506435

Article citations

Data 

Data behind the article

This data has been text mined from the article, or deposited into data resources.

Clinical Trials

Similar Articles 

To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation.