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Technical tips, diagnostic yield and safety of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy.

Author information

Affiliations

  • 1. University Malaya Medical Center, University Malaya, Division of Respiratory Medicine, Department of Medicine, Lembah Pantai, Kuala Lumpur, Malaysia.
      Authors
    • Soo CI 1
    (1 author)
  • 2. Queen Elizabeth Hospital, Respiratory Department, Jalan Penampang, Kota Kinabalu, Sabah, Malaysia.
      Authors
    • Huan NC 2
    (1 author)
  • 3. Sarawak General Hospital, Department of Medicine, Division of Respiratory Medicine, Jalan Hospital, Kuching, Sarawak, Malaysia.
      Authors
    • Kho SS 3
    (1 author)

The Medical Journal of Malaysia, 01 Jul 2024, 79(4):490-493
PMID: 39086350 

Abstract 

Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is commonly used to diagnose and stage lung cancer. In clinical practice, cytology specimens from EBUS-TBNA may be low in cellularity, especially with necrotic lesions. Endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) has recently become the preferred method for obtaining histology biopsy. This retrospective cohort study analysed the first 30 patients who have undergone EBUS-TBMC in a tertiary centre in Malaysia. EBUS-TBMC demonstrated a high diagnostic yield and good safety profile. All the samples obtained were adequate for the detection of driver alteration by next-generation sequencing.

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