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Two "turn on" fluorescence probes based on nitroso recognition group for detecting hydrogen sulfide.

Author information

Affiliations

  • 1. Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, PR China.
      Authors
    • Wei BY 1
    • Yue ZM 1
    • Zhao BX 1
    (3 authors)
  • 2. Institute of Developmental Biology, School of Life Science, Shandong University, Qingdao 266237, PR China.
      Authors
    • Chi XH 2
    • Miao JY 2
    (2 authors)
  • 3. Institute of Medical Sciences, The Second Hospital of Shandong University, Jinan 250033, PR China.
      Authors
    • Lin ZM 3
    (1 author)

Spectrochimica acta. Part A, Molecular and Biomolecular Spectroscopy, 31 Aug 2024, 325:125021
https://doi.org/10.1016/j.saa.2024.125021 PMID: 39236571 

Abstract 

Hydrogen sulfide is a vital signaling molecule which holds a pivotal position in numerous biological functions. In this research, two novel "OFF-ON" fluorescence probes named YNO and TNO were designed based on the nitroso recognition group to detect H2S. Both YNO and TNO performed outstanding response rate and linear relationship between the fluorescence intensity and the concentration of H2S. YNO possessed larger Stokes shift and longer emission wavelength. TNO had lower limit of detection. In addition, YNO was successful applied to sense endogenous and exogenous H2S and target endoplasmic reticulum (ER) in Hela cells.

Full text links 

Read article at publisher's site: https://doi.org/10.1016/j.saa.2024.125021

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