Use of the elevated plus maze in the search for novel anxiolytic agents.

Dawson GR; Tricklebank MD

doi:10.1016/s0165-6147(00)88973-7

Use of the elevated plus maze in the search for novel anxiolytic agents.

Dawson GR ¹,

Tricklebank MD

Affiliations

1. Merck, Sharp and Dohme Research Laboratories, Neuroscience Research Centre, Harlow, UK.
Authors
Dawson GR¹
(1 author)

Trends in Pharmacological Sciences, 01 Feb 1995, 16(2):33-36
https://doi.org/10.1016/s0165-6147(00)88973-7 PMID: 7762079

Review

A comment on this article appears in "Benefits of ethological analysis of behaviour." Trends Pharmacol Sci. 1995 Aug;16(8):260-1.

Abstract

No abstract provided.

Full text links

Read article at publisher's site: https://doi.org/10.1016/s0165-6147(00)88973-7

References

Articles referenced by this article (17)

The relation between fear induced by novel stimulation and exploratory behavior.
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Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat.
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Resistance of baseline activity in the elevated plus-maze to exogenous influences.
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Ethological evaluation of the effects of acute and chronic buspirone treatment in the murine elevated plus-maze test: comparison with haloperidol.
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Use of the elevated plus maze in the search for novel anxiolytic agents.

Affiliations

Authors

Abstract

Full text links

References

The relation between fear induced by novel stimulation and exploratory behavior.

An assessment of the elevated X-maze for studying anxiety and anxiety-modulating drugs.

The behavioural properties of CI-988, a selective cholecystokininB receptor antagonist.

Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat.

Anxiogenic stimuli in the elevated plus-maze.

Resistance of baseline activity in the elevated plus-maze to exogenous influences.

Beware the builders: construction noise changes [14C]GABA release and uptake from amygdaloid and hippocampal slices in the rat.

Title not supplied

Ethological evaluation of the effects of acute and chronic buspirone treatment in the murine elevated plus-maze test: comparison with haloperidol.

Title not supplied

Citations & impact

Impact metrics

Citations of article over time

Alternative metrics

Article citations

Investigation of CNS depressant and muscle relaxant effects of the ethnomedicinal plant <i>Macropanax dispermus</i> on Swiss Albino mice and its effect against oxidative stress.

Altered neuronal lactate dehydrogenase A expression affects cognition in a sex- and age-dependent manner.

Nature and nurture: Comparing mouse behavior in classic versus revised anxiety-like and social behavioral assays in genetically or environmentally defined groups.

Rescue of Alzheimer's disease phenotype in a mouse model by transplantation of wild-type hematopoietic stem and progenitor cells.

Promising effect of Geranium robertianum L. leaves and Aloe vera gel powder on Aspirin^®-induced gastric ulcers in Wistar rats: anxiolytic behavioural effect, antioxidant activity, and protective pathways.

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Use of the elevated plus maze in the search for novel anxiolytic agents.

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