Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog.

Motoyama J; Takabatake T; Takeshima K; Hui C

doi:10.1038/ng0298-104

Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog.

Nature Genetics, 01 Feb 1998, 18(2):104-106
https://doi.org/10.1038/ng0298-104 PMID: 9462734

Abstract

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References

Articles referenced by this article (19)

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome.
Hahn H, Wicking C, Zaphiropoulous PG, Gailani MR, Shanley S, Chidambaram A, Vorechovsky I, Holmberg E, Unden AB, Gillies S, Negus K, Smyth I, Pressman C, Leffell DJ, Gerrard B, Goldstein AM, Dean M, Toftgard R, Chenevix-Trench G, [...] Bale AE
Cell, (6):841-851 1996
MED: 8681379
Human homolog of patched, a candidate gene for the basal cell nevus syndrome.
Johnson RL, Rothman AL, Xie J, Goodrich LV, Bare JW, Bonifas JM, Quinn AG, Myers RM, Cox DR, Epstein EH Jr, Scott MP
Science, (5268):1668-1671 1996
MED: 8658145
The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas.
Gailani MR, Stahle-Backdahl M, Leffell DJ, Glynn M, Zaphiropoulos PG, Pressman C, Unden AB, Dean M, Brash DE, Bale AE, Toftgard R
Nat Genet, (1):78-81 1996
MED: 8782823
Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors.
Xie J, Johnson RL, Zhang X, Bare JW, Waldman FM, Cogen PH, Menon AG, Warren RS, Chen LC, Scott MP, Epstein EH Jr
Cancer Res, (12):2369-2372 1997
MED: 9192811
Altered neural cell fates and medulloblastoma in mouse patched mutants.
Goodrich LV, Milenkovic L, Higgins KM, Scott MP
Science, (5329):1109-1113 1997
MED: 9262482
Biochemical evidence that patched is the Hedgehog receptor.
Marigo V, Davey RA, Zuo Y, Cunningham JM, Tabin CJ
Nature, (6605):176-179 1996
MED: 8906794
The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog.
Stone DM, Hynes M, Armanini M, Swanson TA, Gu Q, Johnson RL, Scott MP, Pennica D, Goddard A, Phillips H, Noll M, Hooper JE, de Sauvage F, Rosenthal A
Nature, (6605):129-134 1996
MED: 8906787
Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo.
Bitgood MJ, McMahon AP
Dev Biol, (1):126-138 1995
MED: 7589793
Sonic hedgehog is expressed in epithelial cells during development of whisker, hair, and tooth.
Iseki S, Araga A, Ohuchi H, Nohno T, Yoshioka H, Hayashi F, Noji S
Biochem Biophys Res Commun, (3):688-693 1996
MED: 8579575
Polarizing activity, Sonic hedgehog, and tooth development in embryonic and postnatal mouse.
Koyama E, Yamaai T, Iseki S, Ohuchi H, Nohno T, Yoshioka H, Hayashi Y, Leatherman JL, Golden EB, Noji S, Pacifici M
Dev Dyn, (1):59-72 1996
MED: 9019247

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Hedgehog Signaling in Cortical Development.
Cai E, Barba MG, Ge X
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Hedgehog-Related Mutation Causes Bone Malformations with or without Hereditary Gene Mutations.
Onodera S, Azuma T
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Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development.
Lee J, Kim Y, Ataliotis P, Kim HG, Kim DW, Bennett DC, Brown NA, Layman LC, Kim SH
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Regulation of signaling pathways in hair follicle stem cells.
Wang X, Liu Y, He J, Wang J, Chen X, Yang R
Burns Trauma, 10:tkac022, 04 Jul 2022
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Ptch2 is a Potential Regulator of Mesenchymal Stem Cells.
Juuri E, Tikka P, Domanskyi A, Corfe I, Morita W, Mckinnon PJ, Jandova N, Balic A
Front Physiol, 13:877565, 28 Apr 2022
Cited by: 1 article | PMID: 35574464 | PMCID: PMC9096555
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Data

Data that cites the article

This data has been provided by curated databases and other sources that have cited the article.

Diseases in OMIM

PATCHED, DROSOPHILA, HOMOLOG OF, 2; PTCH2(OMIM - 603673)

Proteins in UniProt (Showing 5 of 19)

SSD domain-containing protein(UniProt - A0A0A6YWC4)
SSD domain-containing protein(UniProt - A0A0A6YWZ4)
Sonic hedgehog(UniProt - B3GAP8)
Patched 2(UniProt - D6RG83)
Patched 2(UniProt - F6XYY1)

Go to all (19) records in UniProt

GlyGen is an international glycobioinformatics knowledgebase funded by The National Institutes of Health to facilitate glycoscience research by integrating diverse kinds of information, including glycomics, genomics, proteomics (and glycoproteomics), cell biology, developmental biology and biochemistry.

https://www.glygen.org/publication/MED/9462734

Mouse Genome Informatics (MGI)

http://www.informatics.jax.org/reference/9462734

Nucleotide sequences in ENA (2)

Mus musculus (house mouse) hypothetical protein(ENA - BAA24691)
Mus musculus ptch2 mRNA, complete cds.(ENA - AB010833)

Search life-sciences literature (45,103,589 articles, preprints and more)

Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog.

Abstract

Full text links

References

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome.

Human homolog of patched, a candidate gene for the basal cell nevus syndrome.

The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas.

Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors.

Altered neural cell fates and medulloblastoma in mouse patched mutants.

Biochemical evidence that patched is the Hedgehog receptor.

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog.

Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo.

Sonic hedgehog is expressed in epithelial cells during development of whisker, hair, and tooth.

Polarizing activity, Sonic hedgehog, and tooth development in embryonic and postnatal mouse.

Citations & impact

Impact metrics

Citations of article over time

Alternative metrics

Smart citations by scite.ai
Explore citation contexts and check if this article has been supported or disputed.
https://scite.ai/reports/10.1038/ng0298-104

Article citations

Hedgehog Signaling in Cortical Development.

Hedgehog-Related Mutation Causes Bone Malformations with or without Hereditary Gene Mutations.

Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development.

Regulation of signaling pathways in hair follicle stem cells.

Ptch2 is a Potential Regulator of Mesenchymal Stem Cells.

Data

Data that cites the article

Diseases in OMIM

Proteins in UniProt (Showing 5 of 19)

Mouse Genome Informatics (MGI)

Nucleotide sequences in ENA (2)

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