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Integrin associated proteins.

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Affiliations

  • 1. Dana-Farber Cancer Institute, Boston, MA 02115, USA.
      Authors
    • Hemler ME 1
    (1 author)

Current Opinion in Cell Biology, 01 Oct 1998, 10(5):578-585
https://doi.org/10.1016/s0955-0674(98)80032-x PMID: 9818167 

Review

Abstract 

Integrin cytoplasmic domains may interact directly with serveral different cytoskeletal proteins and intracellular signaling molecules. Also, integrins interact directly with other transmembrane structures, including transmembrane-4 superfamily (TM4SF) proteins. New evidence suggests that TM4SF proteins may act as linkers between extracellular integrin alpha chain domains and intracellular signaling molecules, such as phosphatidylinositol 4-kinase and protein kinase C.

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Funding 

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NCI NIH HHS (1)

NIGMS NIH HHS (2)