Age first told have fibroids (years), mean (SD) | 33.9 (6.5) | 38.6 (8.2) | 40.4 (6.7) | 37.8 (8.0) |
Age first have fibroid symptoms (years), mean (SD) | 33.4 (7.4) | 37.6 (8.9) | 38.2 (8.6) | 37.1 (9.0) |
Duration of symptoms (years), mean (SD) | 5.1 (6.0) | 7.3 (8.0) | 6.4 (7.8) | 7.5 (7.9) |
Family history of fibroids, n (%) | 258 (57.8) | 376 (50.7) | 59 (48.0) | 82 (52.9) |
Current contraception, n (%) | 278 (62.3) | 502 (67.7) | 97 (78.9) | 96 (61.9) |
Regular, predictable menses, n (%) | 338 (75.8) | 419 (56.5) | 66 (53.7) | 89 (57.4) |
History of anemia, n (%) | 201 (45.1) | 412 (55.6) | 60 (48.8) | 112 (72.3) |
Requiring transfusion, n (%) | 37 (8.3) | 77 (10.4) | 13 (10.6) | 24 (15.5) |
Total fibroid volume (cm3), median (Q1, Q3)a | 293 (120–552) | 132 (33–310) | 5 (1–18) | 154 (74–339) |
Uterine volume (cm3), median (Q1, Q3)a | 586 (300–1024) | 415 (218–786) | 174 (118–256) | 538 (293–949) |
Number of fibroids measured, median (Q1, Q3)a | 2 (1–4) | 2 (1–3) | 1 (1–1) | 2 (1–3) |
Any fibroid symptoms, n (%) | 419 (93.9) | 701 (94.6) | 119 (96.7) | 150 (96.8) |
Bleeding symptoms | 342 (76.7) | 629 (84.9) | 118 (95.9) | 135 (87.1) |
Menses ≥7 days | 204 (45.7) | 448 (60.5) | 92 (74.8) | 95 (61.3) |
Heavy menses | 314 (70.4) | 580 (78.3) | 113 (91.9) | 122 (78.7) |
Bleeding between periods | 182 (40.8) | 386 (52.1) | 59 (48.0) | 76 (49.0) |
Frequent urination | 278 (62.3) | 428 (57.8) | 63 (51.2) | 111 (71.6) |
Nocturia | 250 (56.1) | 440 (59.4) | 68 (55.3) | 105 (67.7) |
Abdominal bloating | 322 (72.2) | 535 (72.2) | 96 (78.0) | 129 (83.2) |
Abdominal/pelvic pressure | 326 (73.1) | 545 (73.5) | 83 (67.5) | 122 (78.7) |
Appear pregnant | 198 (44.4) | 314 (42.4) | 43 (35.0) | 66 (42.6) |
Discomfort during intercourse | 186 (41.7) | 325 (43.9) | 53 (43.1) | 65 (41.9) |
Pelvic pain requiring meds | 161 (36.1) | 358 (48.3) | 57 (46.3) | 73 (47.1) |
Subfertility | 62 (13.9) | 84 (11.3) | 19 (15.4) | 17 (11.0) |
Multiple miscarriages | 15 (3.4) | 37 (5.0) | 13 (10.6) | 10 (6.5) |
Nonmenstrual pain | 40 (9.0) | 104 (14.0) | 30 (24.4) | 19 (12.3) |
Any prior treatment, n (%) | 68 (15.2) | 155 (20.9) | 10 (8.1) | 24 (15.5) |
Abdominal myomectomy | 28 (6.3) | 49 (6.6) | 2 (1.6) | 7 (4.5) |
Hysteroscopic myomectomy | 18 (4.0) | 25 (3.4) | 2 (1.6) | 5 (3.2) |
Laparoscopic/robotic myomectomy | 14 (3.1) | 31 (4.2) | 2 (1.6) | 4 (2.6) |
Vaginal myomectomy | 9 (2.0) | 17 (2.3) | 1 (0.8) | 3 (1.9) |
Focused ultrasound | 2 (0.4) | 6 (0.8) | 0 (0.0) | 0 (0.0) |
Endometrial ablation | 5 (1.1) | 32 (4.3) | 1 (0.8) | 6 (3.9) |
Radiofrequency ablation | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) |
Uterine artery embolization | 3 (0.7) | 23 (3.1) | 1 (0.8) | 1 (0.6) |