Two Pairs of TGF-β Ligands Demonstrate Genetic Interactions in the C. elegans Response to Bacterial Infection.(A) Survival analysis of tig-3(tm2092);tig-2(ok3416) double mutants on P. luminescens bacteria. n values: Control (73), tig-2 (68), tig-3 (67), tig-3;tig-2 (71). (B) Survival analysis of tig-3(tm2092);dbl-1(wk70) double mutants on P. luminescens bacteria. n values: Control (73), dbl-1 (104), tig-3 (101), tig-3;dbl-1 (126). (C) Survival analysis of daf-7(m62);dbl-1(wk70) double mutants on P. luminescens bacteria. n values: Control (107), dbl-1 (117), daf-7 (75), daf-7;dbl-1 (92). For this trial, strains were grown at 15°C to avoid dauer formation by daf-7 mutants and shifted to 20°C at L4 when exposed to pathogen. Statistical analysis done using Log-rank (Mantel-Cox) test. ns p > 0.05; **** p < 0.0001. Black asterisks show significance relative to control, light blue is significance relative to dbl-1, blue-violet is significance relative to tig-2, green-cyan is significance relative to tig-3, and orange is significance relative to daf-7.