PMC full text: | Published online 2024 Aug 1. doi: 10.3389/fonc.2024.1421651
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Characteristics | Total (n = 281) | nCRT (n = 102) | Primary Resection (n = 179) | P |
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Age, yrs, mean (SD) | 54.65 (10.38) | 51.87 (8.47) | 56.23 (11.03) | 0.001** |
Gender | 281 | 102 | 179 | 0.697 |
Male | 190 (67.6%) | 67 (65.7%) | 123 (68.7%) | |
Female | 91 (32.4%) | 35 (34.3%) | 56 (31.3%) | |
BMI, kg/m2, mean (SD) | 22.55 (2.74) | 22.58 (3.10) | 22.54 (2.53) | 0.914 |
NLR, mean (SD), mean (SD) | 2.72 (2.28) | 2.70 (2.31) | 2.72 (2.27) | 0.937 |
Monocytes,109/L | 0.45 (0.17) | 0.49 (0.18) | 0.42 (0.16) | 0.001** |
Albumin, g/L, mean (SD) | 41.63 (4.50) | 42.57 (3.90) | 41.09 (4.74) | 0.008** |
CEA ng/ml, mean (SD) | 10.45 (14.19) | 7.91 (11.28) | 11.90 (15.45) | 0.023 * |
Clinical stage | <0.001*** | |||
II | 92 (32.7%) | 15 (14.7%) | 77 (43.0%) | |
III | 189 (67.3%) | 87 (85.3%) | 102 (57.0%) | |
Clinical T stage | 0.515 | |||
T2 | 13 (4.6%) | 4 (3.9%) | 9 (5.0%) | |
T3 | 159 (56.6%) | 54 (52.9%) | 105 (58.7%) | |
T4 | 109 (38.8%) | 44 (43.1%) | 65 (36.3%) | |
Clinical N stage | <0.001*** | |||
N0 | 92 (32.7%) | 15 (14.7%) | 77 (43.0%) | |
N1 | 76 (27.1%) | 21 (20.6%) | 55 (30.7%) | |
N2 | 113 (40.2%) | 66 (64.7%) | 47 (26.3%) | |
ypT/pT stage | <0.001*** | |||
T0 | 15 (5.3%) | 15 (14.7%) | – | |
T1 | 4 (1.5%) | 4 (3.9%) | – | |
T2 | 51 (18.1%) | 42 (41.2%) | 9 (5.0%) | |
T3 | 140 (49.8%) | 35 (34.3%) | 105 (58.7%) | |
T4 | 71 (25.3%) | 6 (5.9%) | 65 (36.3%) | |
ypN/pN stage | <0.001*** | |||
N0 | 150 (53.4%) | 73 (71.6%) | 77 (43.0%) | |
N1 | 74 (26.3%) | 19 (18.6%) | 55 (30.7%) | |
N2 | 57 (20.3%) | 10 (9.8%) | 47 (26.3%) | |
VAT, cm2 | 83.02 (56.78) | 89.19 (67.22) | 79.51 (49.72) | 0.170 |
aSAT, cm2 | 98.41 (51.98) | 106.07 (58.28) | 94.04 (47.64) | 0.062 |
gSAT, cm2 | 130.64 (49.90) | 127.85 (56.80) | 132.23 (45.60) | 0.480 |
VSR | 0.93 (0.63) | 0.90 (0.62) | 0.95 (0.64) | 0.569 |
Continuous variables were expressed as mean and standard deviation (SD), categorical variables were expressed as numbers (percentages).
BMI, body mass index; NLR, Neutrophil to Lymphocyte Ratio; SD, standard deviation; VAT, visceral adipose tissue; aSAT, abdominal subcutaneous adipose tissue; gSAT, gluteal subcutaneous adipose tissue; VSR, the ratio of VAT to aSAT. “*” represents a p-value of less than 0.05, “**” represents a p-value of less than 0.01, “***” represents a p-value of less than 0.0001.