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Table 1.

Patient Characteristics by Cohort
CharacteristicPre–vaccine availabilityVaccinatedUnvaccinated
No. (%)COVID-19 diagnosesNo. (%)COVID-19 diagnosesNo. (%)COVID-19 diagnoses
Total, No.18 648 6061 012 33514 035 286866 4693 242 215149 745
Sex
Female9 363 710 (50.2)543 5137 308 556 (52.1)481 5811 363 401 (42.1)79 179
Male9 284 896 (49.8)468 8256 726 730 (47.9)384 8911 878 814 (57.9)70 569
Age range, y
18-293 278 187 (17.6)244 8391 760 740 (12.5)94 533981 925 (30.3)40 131
30-393 225 998 (17.3)203 9311 958 328 (14)149 193966 470 (29.8)50 655
40-493 059 107 (16.4)190 0652 206 560 (15.7)236 229612 180 (18.9)33 429
50-593 264 621 (17.5)184 3712 716 818 (19.4)204 009376 272 (11.6)16 827
60-692 552 894 (13.7)92 9312 316 757 (16.5)105 645186 402 (5.7)5625
70-792 066 329 (11.1)51 5731 980 447 (14.1)54 05780 546 (2.5)1947
80-89989 819 (5.3)31 893909 927 (6.5)18 32730 138 (0.9)903
≥90211 651 (1.1)12 717185 709 (1.3)44798282 (0.3)225
Ethnicitya
Black1 191 793 (6.4)118 365789 476 (5.6)41 457325 199 (10)9609
South Asian217 132 (1.2)14 241128 514 (0.9)752181 017 (2.5)3867
White14 865 866 (79.7)773 74511 752 297 (83.7)748 7432 025 492 (62.5)115 449
Mixed423 111 (2.3)20 301237 383 (1.7)10 641190 874 (5.9)4035
Otherb400 437 (2.1)27 069217 317 (1.5)9585173 014 (5.3)7641
Missing1 550 267 (8.3)58 611910 299 (6.5)48 513446 619 (13.8)9141
IMD quintile
13 574 653 (19.2)247 3652 273 863 (16.2)135 945958 877 (29.6)45 795
23 690 808 (19.8)219 0632 617 493 (18.6)158 889775 318 (23.9)35 445
34 042 896 (21.7)203 0553 111 723 (22.2)186 855652 380 (20.1)29 619
43 809 548 (20.4)183 0153 065 889 (21.8)191 499498 458 (15.4)22 515
53 530 701 (18.9)159 8372 966 318 (21.1)193 275357 182 (11)16 371
Smoking
Never759 965 (4.1)40 677428 549 (3.1)16 419370 770 (11.4)8415
Formerly8 568 556 (45.9)504 8436 540 674 (46.6)422 3371 348 307 (41.6)59 631
Currently6 137 311 (32.9)329 3735 106 300 (36.4)333 675645 817 (19.9)43 887
Missing3 182 774 (17.1)137 4391 959 763 (14)94 035877 321 (27.1)37 815
Region
East4 305 743 (23.1)227 4213 281 525 (23.4)182 847731 831 (22.6)33 825
East Midlands3 263 511 (17.5)191 9252 474 916 (17.6)161 259527 562 (16.3)28 815
London1 245 392 (6.7)67 791728 567 (5.2)37 287459 504 (14.2)10 977
North East889 507 (4.8)60 369663 394 (4.7)48 891137 238 (4.2)7239
North West1 658 370 (8.9)109 8871 270 319 (9.1)88 227220 722 (6.8)12 045
South East1 249 245 (6.7)50 373969 482 (6.9)57 105195 663 (6)8853
South West2 655 179 (14.2)80 6492 207 972 (15.7)133 143331 576 (10.2)17 871
West Midlands760 648 (4.1)56 397499 564 (3.6)29 931181 504 (5.6)8223
Yorkshire2 621 011 (14.1)167 5051 939 547 (13.8)127 767456 615 (14.1)21 891
Care home resident90 076 (0.5)15 30957 532 (0.4)28353014 (0.1)105

Abbreviation: IMD, Index of Multiple Deprivation (lower indicates more deprived).

a Ethnicity data were reported because disparities in COVID-19 outcomes by ethnic group have been reported.17
b Other ethnicity groups were consolidated for disclosure control.